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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/62499
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dc.creatorTarso Magno Leiteribeiropt_BR
dc.creatorVitor Nunes Arantespt_BR
dc.creatorJonas Augusto Ramospt_BR
dc.creatorPeter v Draganovpt_BR
dc.creatorDennis Yangpt_BR
dc.creatorRoberto Gardone Guimarãespt_BR
dc.date.accessioned2024-01-08T22:44:44Z-
dc.date.available2024-01-08T22:44:44Z-
dc.date.issued2021-
dc.citation.volume58pt_BR
dc.citation.issue2pt_BR
dc.citation.spage195pt_BR
dc.citation.epage201pt_BR
dc.identifier.doi10.1590/s0004-2803.202100000-35pt_BR
dc.identifier.issn16784219pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/62499-
dc.description.resumoBackground – Endoscopic submucosal dissection (ESD) of esophageal superficial neoplasm is associated with a high en bloc R0 resection rate and low recurrence. Objective – We aim to compare the performance and clinical outcomes of ESD via ESD after circumferential incision (ESD-C) versus submucosal tunneling (ESD-T). Methods – Single-center retrospective analysis of all consecutive patients who underwent ESD for superficial esophageal cancer, between 2009 and 2018. ESD-T was defined as the technique of making the mucosal incisions followed by submucosal tunneling in the oral to anal direction. ESD-C consisted of completing a circumferential incision followed by ESD. Main study outcomes included en bloc and R0 resection rates. Secondary outcomes included procedural characteristics, curative resection rate, local recurrence and adverse events. Results – A total of 65 procedures (23 ESD-T and 42 ESD-C) were performed for ESCC (40; 61.5%) and BE-neoplasia (25; 38.5%). There were no statistically significant differences between patients who underwent ESD-T versus ESD-C in en bloc (91.3% vs 100%, P=0.12), R0 (65.2% vs 78.6%, P=0.24), curative resection rates (65.2% vs 73.8%, P=0.47) and mean procedure time (118.7 min with vs 102.4 min, P=0.35). Adverse events for ESD-T and ESD-C were as follows: bleeding (0 versus 2.4%; P=0.53), perforation (4.3% vs 0; P=0.61), esophageal stricture (8.7% versus 9.5%; P=0.31). Local recurrence was encountered in 8.7% after ESD-T and 2.4% after ESD-C (P=0.28) at a mean follow-up of 8 and 2.75 years, respectively (P=0.001). Conclusion:– ESD-T and ESD-C appear to be equally effective with similar safety profiles for the management of superficial esophageal neoplasmspt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE CIRURGIApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofArquivos de Gastroenterologia-
dc.rightsAcesso Abertopt_BR
dc.subjectEndoscopic Mucosal Resectionpt_BR
dc.subjectSuperficial esophageal neoplasmpt_BR
dc.subjectEsophageal Neoplasmspt_BR
dc.subjectNeoplasms, Squamous Cellpt_BR
dc.subject.otherEndoscopic Mucosal Resectionpt_BR
dc.subject.otherEsophageal Neoplasmspt_BR
dc.subject.otherNeoplasms, Squamous Cellpt_BR
dc.subject.otherBarrett Esophaguspt_BR
dc.titleEndoscopic submucosal dissection with circumferential incision versus tunneling method for treatment of superficial esophageal cancerpt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://doi.org/10.1590/S0004-2803.202100000-35pt_BR
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