Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/62522
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dc.creatorSander Luis Gomes Pimentelpt_BR
dc.creatorRodrigo Tavares Lanna Rochapt_BR
dc.creatorRenan Mello Oliveirapt_BR
dc.creatorMárcia de Melo Barbosapt_BR
dc.creatorCraig Sablept_BR
dc.creatorAntonio Luiz Pinho Ribeiropt_BR
dc.creatorAndrea Zawacki Beatonpt_BR
dc.creatorMaria Carmo Pereira Nunespt_BR
dc.creatorBruno Ramos Nascimentopt_BR
dc.creatorJuliane Francopt_BR
dc.creatorKaciane Krauss Bruno Oliveirapt_BR
dc.creatorClara Leal Fragapt_BR
dc.creatorFrederico Vargas Botinha de Macedopt_BR
dc.creatorLeonardo Arruda de Moraes Rasopt_BR
dc.creatorRenata Eliane de Ávilapt_BR
dc.creatorLuiza Pereira Afonso Dos Santospt_BR
dc.date.accessioned2024-01-09T19:37:45Z-
dc.date.available2024-01-09T19:37:45Z-
dc.date.issued2021-
dc.citation.volume54pt_BR
dc.citation.issue(e0382-2021pt_BR
dc.citation.spage1pt_BR
dc.citation.epage9pt_BR
dc.identifier.doi10.1590/0037-8682-0382-2021pt_BR
dc.identifier.issn16789849pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/62522-
dc.description.resumoIntroduction: Cardiac involvement seems to impact prognosis of COVID-19, being more frequent in critically ill patients. We aimed to assess the prognostic value of right ventricular (RV) and left ventricular (LV) dysfunction, evaluated by bedside echocardiography (echo), in patients hospitalized with COVID-19. Methods: Patients admitted in 2 reference hospitals in Brazil from Jul to Sept/2020 with confirmed COVID-19 and moderate/severe presentations underwent clinical and laboratory evaluation, and focused bedside echo (GE Vivid-IQ), at the earliest convenience, with remote interpretation. The association between demographics, clinical comorbidities and echo variables with all-cause hospital mortality was assessed, and factors significant at p<0.10 were put into multivariable models. Results: Total 163 patients were enrolled, 59% were men, mean age 64±16 years, and 107 (66%) were admitted to intensive care. Comorbidities were present in 144 (88%) patients: hypertension 115 (71%), diabetes 61 (37%) and heart failure 22 (14%). In-hospital mortality was 34% (N=56). In univariate analysis, echo variables significantly associated with death were: LV ejection fraction (LVEF, OR=0.94), RV fractional area change (OR=0.96), tricuspid annular plane systolic excursion (TAPSE, OR=0.83) and RV dysfunction (OR=5.3). In multivariate analysis, after adjustment for clinical and demographic variables, independent predictors of mortality were age≥63 years (OR=5.53, 95%CI 1.52–20.17), LVEF<64% (OR=7.37, 95%CI 2.10–25.94) and TAPSE<18.5 mm (OR=9.43, 95% CI 2.57–35.03), and the final model had good discrimination, with C-statistic=0.83 (95%CI 0.75–0.91). Conclusion: Markers of RV and LV dysfunction assessed by bedside echo are independent predictors of mortality in hospitalized COVID-19 patients, after adjustment for clinical variables.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE CLÍNICA MÉDICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofRevista da Sociedade Brasileira de Medicina Tropical-
dc.rightsAcesso Abertopt_BR
dc.subjectCOVID-19pt_BR
dc.subjectEchocardiographypt_BR
dc.subjectPrognosispt_BR
dc.subjectSARS-CoV-2pt_BR
dc.subjectMortalitypt_BR
dc.subject.otherCOVID-19pt_BR
dc.subject.otherEchocardiographypt_BR
dc.subject.otherPrognosispt_BR
dc.subject.otherSARS-CoV-2pt_BR
dc.subject.otherMortalitypt_BR
dc.titleBedside echocardiography to predict mortality of covid-19 patients beyond clinical data: data from the provar-covid studypt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://doi.org/10.1590/0037-8682-0382-2021pt_BR
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