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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/62980
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dc.creatorClaudio Joséaugustopt_BR
dc.creatorWania da Silva Carvalhopt_BR
dc.creatorIsabela Neves de Almeidapt_BR
dc.creatorLida Jouca de Assis Figueiredopt_BR
dc.creatorNayane g. t. Dantaspt_BR
dc.creatorPhilip n Suffyspt_BR
dc.creatorSilvana Spindola de Mirandapt_BR
dc.date.accessioned2024-01-17T19:14:55Z-
dc.date.available2024-01-17T19:14:55Z-
dc.date.issued2017-
dc.citation.volume49pt_BR
dc.citation.spage641pt_BR
dc.citation.epage646pt_BR
dc.identifier.issn15178382pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/62980-
dc.description.resumoDNA genotyping of Mycobacterium tuberculosis has been widely applied in the understanding of disease transmission in many countries. The purpose of this study was to genotype the strains of M. tuberculosis isolated in patients with new tuberculosis (TB) cases in Minas Gerais, as well as to compare the similarity, discriminatory power, and agreement of the clusters between the IS6110 Restriction Fragment Length Polymorfism (RFLP) and 12 loci Variable Number Tandem Repeat – Mycobacterial Interspersed Repetitive Units (MIRU-VNTR) tech niques. It was observed that 32% (66/204) of the isolated strains in the RFLP-IS6110 and 50.9% (104/204) of the isolated strains in the MIRU-VNTR presented a similarity of equal to or above 85%. The RFLP-IS6110 and MIRU-VNTR proved to contain a high discriminatory power. The similarity index resulting from the RFLP showed no recent transmission. Good agreement was observed between the techniques when clusters were detected; however,the best epidemiological relationship was found when using the RFLP-IS6110.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAR - DEPARTAMENTO DE FARMÁCIA SOCIALpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofBrazilian Journal of Microbiology-
dc.rightsAcesso Abertopt_BR
dc.subjectMycobacterium tuberculosispt_BR
dc.subjectPolymorphism, Restriction Fragment Lengthpt_BR
dc.subject.otherMycobacterium tuberculosispt_BR
dc.subject.otherPolymorphism, Restriction Fragment Lengthpt_BR
dc.titleComparative study of RFLP-IS6110 and MIRU-VNTR from Mycobacterium tuberculosis isolated in the state of Minas Gerais, Brazilpt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://doi.org/10.1016/j.bjm.2017.04.015pt_BR
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