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http://hdl.handle.net/1843/62981
Type: | Artigo de Periódico |
Title: | Circulating tumour cells in head and neck cancers: biological insights |
Authors: | Vishal Rao Ricardo Santiago Gomez Peter Brennan Gururaj Arakeri Anand Subash Ritvi Bagadia Shalini Thakur Akshay Kudpaje Ravi Nayar Shekar Patil Felipe Paiva Fonseca |
Abstract: | Tumour metastasis is one of the leading cause of cancer-related mortality. Circulating tumour cells (CTCs) have been implicated in loco-regional and distant metastasis and its role is being extensively studied in various malignancies, including those from the head and neck region. The main challenge in understanding their significance lies in the rarity of these cells in the blood. However, newer technologies have attempted to overcome these pitfalls. This review explores the evolution of CTC research and other related areas, including its biological significance, sustainability within the circulating vascular environment and possible clinical implications. |
Subject: | Biomarkers Neoplasms Neoplastic cells, circulating Head and neck neoplasms |
language: | eng |
metadata.dc.publisher.country: | Brasil |
Publisher: | Universidade Federal de Minas Gerais |
Publisher Initials: | UFMG |
metadata.dc.publisher.department: | FAO - DEPARTAMENTO DE CLÍNICA |
Rights: | Acesso Restrito |
metadata.dc.identifier.doi: | https://doi.org/10.1111/jop.13075 |
URI: | http://hdl.handle.net/1843/62981 |
Issue Date: | 2020 |
metadata.dc.url.externa: | https://onlinelibrary.wiley.com/doi/10.1111/jop.13075 |
metadata.dc.relation.ispartof: | Journal of oral pathology & medicine |
Appears in Collections: | Artigo de Periódico |
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