Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/63075
Type: Artigo de Periódico
Title: Clinicopathological analysis of oral burkitt's lymphoma in pediatric patients: a systematic review
Authors: Carla Isabelly Rodrigues-Fernandes
Maria Eduarda Pérez-de-Oliveira
Lady Paola Aristizabal Arboleda
Felipe Paiva Fonseca
Márcio Ajudarte Lopes
Pablo Agustin Vargas
Alan Roger Santos-Silva
Abstract: The aim of this study was to integrate the available data regarding pediatric Burkitt's lymphoma (BL) of the oral cavity. A systematic review was conducted following PRISMA guidelines, through a specific search strategy. Twenty-nine publications were included in this study, resulting in a total of 144 cases. Oral BL was predominantly found in males (75.7%). The mandible was the most involved site (37.5%), and all cases clinically exhibited a swelling. Presence of EBV was observed in 33.3% of the cases, and 4 cases reported HIV-positive patients (33.3%). Chemotherapy was the leading treatment choice for oral BL (94.9%), and the overall 5-year survival was 54.3%. Regarding the quality assessment of the studies, most (19 studies; 65.5%) were classified as an overall moderate risk of bias. In conclusion, the clinicopathological characteristics of oral BL in the pediatric population comprise the sporadic and intermediate subtypes. Despite its aggressiveness, this malignancy presents a moderate overall survival.
Subject: Burkitt lymphoma
Mandible
Maxilla
Mouth
Edema
Neoplasms
Drug therapy
language: eng
metadata.dc.publisher.country: Brasil
Publisher: Universidade Federal de Minas Gerais
Publisher Initials: UFMG
metadata.dc.publisher.department: FAO - DEPARTAMENTO DE CLÍNICA
Rights: Acesso Restrito
metadata.dc.identifier.doi: https://doi.org/10.1016/j.ijporl.2020.110033
URI: http://hdl.handle.net/1843/63075
Issue Date: Jul-2020
metadata.dc.url.externa: https://www.sciencedirect.com/science/article/pii/S0165587620301762?via%3Dihub
metadata.dc.relation.ispartof: International journal of pediatric otorhinolaryngology
Appears in Collections:Artigo de Periódico

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