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http://hdl.handle.net/1843/63075
Type: | Artigo de Periódico |
Title: | Clinicopathological analysis of oral burkitt's lymphoma in pediatric patients: a systematic review |
Authors: | Carla Isabelly Rodrigues-Fernandes Maria Eduarda Pérez-de-Oliveira Lady Paola Aristizabal Arboleda Felipe Paiva Fonseca Márcio Ajudarte Lopes Pablo Agustin Vargas Alan Roger Santos-Silva |
Abstract: | The aim of this study was to integrate the available data regarding pediatric Burkitt's lymphoma (BL) of the oral cavity. A systematic review was conducted following PRISMA guidelines, through a specific search strategy. Twenty-nine publications were included in this study, resulting in a total of 144 cases. Oral BL was predominantly found in males (75.7%). The mandible was the most involved site (37.5%), and all cases clinically exhibited a swelling. Presence of EBV was observed in 33.3% of the cases, and 4 cases reported HIV-positive patients (33.3%). Chemotherapy was the leading treatment choice for oral BL (94.9%), and the overall 5-year survival was 54.3%. Regarding the quality assessment of the studies, most (19 studies; 65.5%) were classified as an overall moderate risk of bias. In conclusion, the clinicopathological characteristics of oral BL in the pediatric population comprise the sporadic and intermediate subtypes. Despite its aggressiveness, this malignancy presents a moderate overall survival. |
Subject: | Burkitt lymphoma Mandible Maxilla Mouth Edema Neoplasms Drug therapy |
language: | eng |
metadata.dc.publisher.country: | Brasil |
Publisher: | Universidade Federal de Minas Gerais |
Publisher Initials: | UFMG |
metadata.dc.publisher.department: | FAO - DEPARTAMENTO DE CLÍNICA |
Rights: | Acesso Restrito |
metadata.dc.identifier.doi: | https://doi.org/10.1016/j.ijporl.2020.110033 |
URI: | http://hdl.handle.net/1843/63075 |
Issue Date: | Jul-2020 |
metadata.dc.url.externa: | https://www.sciencedirect.com/science/article/pii/S0165587620301762?via%3Dihub |
metadata.dc.relation.ispartof: | International journal of pediatric otorhinolaryngology |
Appears in Collections: | Artigo de Periódico |
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