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http://hdl.handle.net/1843/63164| Type: | Artigo de Periódico |
| Title: | Structural elucidation and free radical scavenging activity of a new-orsellinic acid derivative isolated from the lichen Cladonia rappii |
| Authors: | Tiago Coelho de Assis Lage Lívia Pereira Horta Ricardo Marques Montanari Jefferson Guilherme da Silva Angelo de Fatima Sergio Antonio Fernandes Luzia Valentina Modolo |
| Abstract: | Rappiidic acid, a new o-orsellinic acid derivative, was isolated from the lichen Cladonia rappii. Its capability to scavenge reactive oxygen species (ROS) and reactive nitrogen species (RNS) was investigated and compared with resveratrol and (+)-usnic acid. Usnic acid at 100 μM was the most efficient ROS scavenger, exhibiting activity 3-fold higher than that of resveratrol. At the same concentration, rappidic acid scavenged 23.1% of ROS formed, demonstratingthat this compound is twice as active as resveratrol. Both compounds were shown to be poor RNS scavengers. |
| Subject: | Produtos naturais Superóxido Cladoniacea Espectroscopia de ressonância nuclear Cromatografia liquida Ácidos |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | ICB - DEPARTAMENTO DE BOTÂNICA ICX - DEPARTAMENTO DE QUÍMICA |
| Rights: | Acesso Aberto |
| metadata.dc.identifier.doi: | https://doi.org/10.1177/1934578X1601100932 |
| URI: | http://hdl.handle.net/1843/63164 |
| Issue Date: | 2016 |
| metadata.dc.url.externa: | https://journals.sagepub.com/doi/abs/10.1177/1934578X1601100932 |
| metadata.dc.relation.ispartof: | Natural Product Communications |
| Appears in Collections: | Artigo de Periódico |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| Structural-elucidation-and-free-radical-scavenging-activity-of-a-new-o-orsellinic-acid-derivative lage-et-al-2016.pdf | 292.83 kB | Adobe PDF | View/Open |
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