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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/63174
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dc.creatorLaura Luiza Menezessantospt_BR
dc.creatorMaria de Fátima Haueisen Sander Dinizpt_BR
dc.creatorAlessandra Carvalho Goulartpt_BR
dc.creatorSandhi Maria Barretopt_BR
dc.creatorRoberta Carvalho Figueiredopt_BR
dc.date.accessioned2024-01-19T21:35:59Z-
dc.date.available2024-01-19T21:35:59Z-
dc.date.issued2022-
dc.citation.volume140pt_BR
dc.citation.issue2pt_BR
dc.citation.spage213pt_BR
dc.citation.epage221pt_BR
dc.identifier.doi10.1590/1516-3180.2021.0095.r2.22062021pt_BR
dc.identifier.issn18069460pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/63174-
dc.description.resumoACKGROUND: Non-alcoholic fatty liver disease (NAFLD) has become a public health problem worldwide. Neck circumference (NC) is a simple anthropometric adiposity parameter that has been correlated with cardiometabolic disorders like NAFLD. OBJECTIVES: To investigate the association between NC and NAFLD, considering their obesity-modifying effect, among participants from the Longitudinal Study of Adult Health (ELSA-Brasil) baseline study. DESIGN AND SETTINGS: Cross-sectional study at the ELSA-Brasil centers of six public research ins titutions. METHODS: This analysis was conducted on 5,187 women and 4,270 men of mean age 51.8 (± 9.2) years. Anthropometric indexes (NC, waist circumference [WC] and body mass index [BMI]), biochemical and clinical parameters (diabetes, hypertension and dyslipidemia) and hepatic ultrasound were measured. The association between NC and NAFLD was estimated using multinomial logistic regression, considering potential confounding effects (age, WC, diabetes, hypertension and dyslipidemia). Effect modification was investigated by including the interaction term NC x BMI in the final model. RESULTS: The frequency of NAFLD and mean value of NC were 33.6% and 33.9 (± 2.5) cm in women, and 45.8% and 39.4 (± 2.8) cm in men, respectively. Even after all adjustments, larger NC was associated with a greater chance of moderate/severe NAFLD (1.16; 95% confidence interval [CI] for women; 1.05, 95% CI for men; P < 0.001). Presence of multiplicative interaction between NC and BMI (P < 0.001) was also observed. CONCLUSION: NC was positively associated with NAFLD in both sexes, regardless of traditional adiposity indexes such as BMI and WC. The magnitude of the association was more pronounced among women.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE MEDICINA PREVENTIVA SOCIALpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofSao Paulo Medical Journal-
dc.rightsAcesso Abertopt_BR
dc.subjectLiver Diseasespt_BR
dc.subjectNeckpt_BR
dc.subjectBody Compositionpt_BR
dc.subjectAdipose Tissuept_BR
dc.subjectWeights and Measurespt_BR
dc.subject.otherLiver Diseasespt_BR
dc.subject.otherNeckpt_BR
dc.subject.otherBody Compositionpt_BR
dc.subject.otherAdipose Tissuept_BR
dc.subject.otherWeights and Measurespt_BR
dc.titleAssociation between neck circumference and non-alcoholic fatty liver disease: cross-sectional analysis from elsa-brasilpt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://doi.org/10.1590/1516-3180.2021.0095.R2.22062021pt_BR
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