Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/63262
Type: Artigo de Periódico
Title: Reduction in pregnancies and litters in mice couples with splenectomized male
Authors: Dalton Munizsantos
Gisele Araújo Pereira
Kelly Renata Sabino
Andy Petroianu
Abstract: Purpose: The spleen is relevant in blood purification, hematopoiesis, metabolism, and immune response to antigens, in addition to the storage and control on the release of metals and amino acids. Its functions concerning reproduction characteristics are still unknown. The objective was to study the influence of splenectomies on reproduction. Methods: This study analyzed 25 mice couples, distributed into five groups: group 1 – control, no surgery: group 2 – control, submitted to laparotomy and laparorrhaphy only; group 3 splenectomy in male mice; group 4 – splenectomy in female mice; group 5 – splenectomy in male and female mice. The animals were studied as regards the number of gestations and offspring generated in each gestation. Results: A decrease in both the number of gestations and the number of offspring was verified in the male mice that had received a splenectomy when coupled with normal female mice. It is important to emphasize lower reproduction level when paired asplenic males with normal females, otherwise, the couples in which both mice had been splenectomized did not present change in the reproduction pattern. Conclusion: A reduction in the number of pregnancies and litters occurs in mice couples when the male mice were previously splenectomized.
Subject: Spleen
Reproduction
Splenectomy
Sexual disfunction
Fertility
language: eng
metadata.dc.publisher.country: Brasil
Publisher: Universidade Federal de Minas Gerais
Publisher Initials: UFMG
metadata.dc.publisher.department: MED - DEPARTAMENTO DE CIRURGIA
Rights: Acesso Aberto
metadata.dc.identifier.doi: 10.1590/acb360201
URI: http://hdl.handle.net/1843/63262
Issue Date: 2021
metadata.dc.url.externa: https://doi.org/10.1590/ACB360201
metadata.dc.relation.ispartof: Acta Cirúrgica Brasileira
Appears in Collections:Artigo de Periódico

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