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http://hdl.handle.net/1843/63288| Type: | Artigo de Periódico |
| Title: | Preemptive effect of dexamethasone in third-molar surgery: a meta-analysis |
| Authors: | Saulo Gabriel Moreira Falci Thiago César Lima Carolina de Castro Martins Cássio Roberto Rocha dos Santos Marcos Luciano Pimenta Pinheiro |
| Abstract: | The aim of the present study was to assess the effectiveness of preemptive dexamethasone in surgery of the lower third molars and to compare it with other oral anti-inflammatories. An electronic search was conducted for preemptive effects related to lower third-molar surgery in 3 separate databases. The variables pain, swelling, and trismus were assessed. Meta-analysis was used to calculate the pooled effect measures for mean and standard deviation values (95% confidence interval [CI]). Seven split-mouth clinical trials were selected. Two studies were included in the meta-analysis. Three studies showed a low risk of bias; 2 studies exhibited a moderate risk and 2 a high risk of bias. Dexamethasone was better than nonsteroidal anti-inflammatories for preemptive effectiveness. Meta-analysis for swelling confirmed better results for dexamethasone than for methylprednisolone after 2 days (95% CI = −1.28 to −0.38), 4 days (95% CI = −1.65 to −0.71), 7 days (95% CI = −1.42 to −0.71), and overall (95% CI = −1.25 to −0.72). Dexamethasone was better than methylprednisolone for mouth opening after 4 days (95% CI = 0.18 to 1.07). There is insufficient evidence through meta-analysis to conclude that dexamethasone is better than other nonsteroidal anti-inflammatories or methylprednisolone as a preemptive analgesic. The results of this meta-analysis suggest that dexamethasone is more effective than methylprednisolone for swelling and trismus. |
| Subject: | Molar, third Surgery, oral Dexamethasone Meta-analysis |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | FAO - DEPARTAMENTO DE ODONTOPEDIATRIA E ORTODONTIA |
| Rights: | Acesso Restrito |
| metadata.dc.identifier.doi: | https://doi.org/10.2344/anpr-64-05-08 |
| URI: | http://hdl.handle.net/1843/63288 |
| Issue Date: | 2017 |
| metadata.dc.url.externa: | https://anesthesiaprogress.kglmeridian.com/view/journals/anpr/64/3/article-p136.xml |
| metadata.dc.relation.ispartof: | Anesthesia Progress |
| Appears in Collections: | Artigo de Periódico |
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