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http://hdl.handle.net/1843/63456
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DC Field | Value | Language |
---|---|---|
dc.creator | Alice Machado-Silva | pt_BR |
dc.creator | Danielle Passos-Silva | pt_BR |
dc.creator | Robson Augusto Souza dos Santos | pt_BR |
dc.creator | Rubén Dario Sinisterra Millán | pt_BR |
dc.date.accessioned | 2024-01-29T14:05:40Z | - |
dc.date.available | 2024-01-29T14:05:40Z | - |
dc.date.issued | 2016 | - |
dc.citation.volume | 26 | pt_BR |
dc.citation.issue | 6 | pt_BR |
dc.citation.spage | 669 | pt_BR |
dc.citation.epage | 678 | pt_BR |
dc.identifier.doi | https://doi.org/10.1080/13543776.2016.1179283 | pt_BR |
dc.identifier.issn | 1744-7674 | pt_BR |
dc.identifier.uri | http://hdl.handle.net/1843/63456 | - |
dc.description.resumo | Introduction: Angiotensin-(1-7) is a key component of the Renin-Angiotensin System, which can counter-regulate several deleterious effects caused by angiotensin II. Due to the potential for therapeutic use, several of its actions are specifically described in patents. Areas covered: In this review, the authors describe a plethora of therapeutic uses for Angiotensin-(1-7), claimed and supported by experimental evidence in patent documents and applications. Expert opinion: The clinical potential of Angiotensin-(1-7) as a therapeutic agent to treat several pathologies is evidenced by the variety of patents and clinical trials involving this peptide. Cancer treatment is one of the most advanced therapeutic areas, but clinical studies are also available in several other areas, such as cardiovascular, hematological, transplantation, surgical and medical procedures. | pt_BR |
dc.description.sponsorship | CNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico | pt_BR |
dc.description.sponsorship | FAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais | pt_BR |
dc.description.sponsorship | INCT – Instituto nacional de ciência e tecnologia (Antigo Instituto do Milênio) | pt_BR |
dc.description.sponsorship | Outra Agência | pt_BR |
dc.language | eng | pt_BR |
dc.publisher | Universidade Federal de Minas Gerais | pt_BR |
dc.publisher.country | Brasil | pt_BR |
dc.publisher.department | ICB - DEPARTAMENTO DE FISIOLOGIA E BIOFÍSICA | pt_BR |
dc.publisher.department | ICX - DEPARTAMENTO DE QUÍMICA | pt_BR |
dc.publisher.initials | UFMG | pt_BR |
dc.relation.ispartof | Expert Opinion on Therapeutic Patents | pt_BR |
dc.rights | Acesso Restrito | pt_BR |
dc.subject | Angiotensin (1-7) | pt_BR |
dc.subject | Arg0 | pt_BR |
dc.subject | Mas receptor | pt_BR |
dc.subject | PanCyte | pt_BR |
dc.subject | TXA-127 | pt_BR |
dc.subject | RAS | pt_BR |
dc.subject.other | Angiotensina - Uso terapêutico | pt_BR |
dc.subject.other | Sistema renina-angiotensina | pt_BR |
dc.subject.other | Patentes | pt_BR |
dc.subject.other | Câncer - Tratamento | pt_BR |
dc.title | Therapeutic uses for Angiotensin-(1-7) | pt_BR |
dc.type | Artigo de Periódico | pt_BR |
dc.url.externa | https://www.tandfonline.com/doi/full/10.1080/13543776.2016.1179283 | pt_BR |
dc.identifier.orcid | https://orcid.org/0000-0001-7656-1849 | pt_BR |
Appears in Collections: | Artigo de Periódico |
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