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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/63703
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dc.creatorErison-Santana Santospt_BR
dc.creatorCarla-Isabelly Rodrigues-Fernandespt_BR
dc.creatorJoab-Cabral Cabralpt_BR
dc.creatorFelipe Paiva Fonsecapt_BR
dc.creatorAdriana-Franco-Paes Lemept_BR
dc.date.accessioned2024-02-02T18:20:22Z-
dc.date.available2024-02-02T18:20:22Z-
dc.date.issued2021-03-01-
dc.citation.volume13pt_BR
dc.citation.issue3pt_BR
dc.citation.spagee295pt_BR
dc.citation.epagee302pt_BR
dc.identifier.doihttps://doi.org/10.4317%2Fjced.56191pt_BR
dc.identifier.issn19895488pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/63703-
dc.description.resumoBackground Ameloblastoma is a locally aggressive tumor, originated from odontogenic epithelium, and affects the jawbones with an elevated recurrence rate. The molecular mechanisms involved with the pathogenesis of this tumor remain undetermined. This review aimed to describe the current data regarding epigenetic alterations in ameloblastoma. Material and Methods A systematized electronic search was performed in the English-language literature in three databases, combining the following keywords: ameloblastoma, epigenetic, methylation, noncoding RNA, histone acetylation. Results According to the gathered results of 11 studies in this review, epigenetic alterations could induce the development and progression of ameloblastoma. DNA methylation has been the most assessed mechanism in ameloblastomas. Conclusions Current literature data indicate that epigenetic events can be involved in the etiopathogenesis of ameloblastomas.pt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofJournal of Clinical and experimental dentistrypt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectTumores odontogênicospt_BR
dc.subjecttítulo periódico: busca dia 27/11/2023 d.c depois de Cristo título periódico Journal of clinical and experimental dentistry assunto ameloblastoma fao clínicapt_BR
dc.subject.otherAmeloblastomapt_BR
dc.subject.otherEpigenomicspt_BR
dc.subject.otherMethylationpt_BR
dc.subject.otherRNA, untranslatedpt_BR
dc.subject.otherEnzymespt_BR
dc.subject.otherAcetylationpt_BR
dc.titleEpigenetic alterations in ameloblastomas: a literature reviewpt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC7920560/pt_BR
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