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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/65379
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dc.creatorLaura Borges Kirschnickpt_BR
dc.creatorVivian Petersen Wagnerpt_BR
dc.creatorFelipe Paiva Fonsecapt_BR
dc.creatorManoela Domingues Martinspt_BR
dc.creatorFelipe Martins Silveirapt_BR
dc.creatorLauren Frenzel Schuchpt_BR
dc.creatorMarco Antonio Martinspt_BR
dc.creatorMárcio Ajudarte Lopespt_BR
dc.creatorAlan Roger dos Santos-Silvapt_BR
dc.creatorVinicius Coelho Carrardpt_BR
dc.creatorJean Nunes dos Santospt_BR
dc.creatorPablo Agustin Vargaspt_BR
dc.date.accessioned2024-03-06T19:18:48Z-
dc.date.available2024-03-06T19:18:48Z-
dc.date.issued2021-
dc.citation.volume50pt_BR
dc.citation.issuespt_BR
dc.citation.spage741pt_BR
dc.citation.epage749pt_BR
dc.identifier.doihttps://doi.org/10.1111/jop.13159pt_BR
dc.identifier.issn09042512pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/65379-
dc.description.resumoBackground: The aim of the present systematic review was to analyze the available data regarding acinic cell carcinoma of the oral and maxillofacial region. Methods: A search strategy was performed using PubMed, Web of Science, Scopus, and Embase electronic databases. Results: Available data revealed a slight female preference (54.73%) and a mean age at diagnosis of 47.51 ± 19.85 years. The parotid glands (67.72%) were most frequently affected, and most cases were asymptomatic (69.54%). A microcystic histopathological pattern was reported in 21.56% of the cases, and the Periodic acid-Schiff was the staining method most frequently used, after the hematoxylin and eosin staining, in the tumors analyzed. The lesions were mainly treated by surgical removal (72.32%). Recurrence was reported in 81 cases (27.83%) and metastasis in 100 (42.91%). Statistical data analysis revealed that tumors located in major salivary glands and exhibiting high-grade histology were associated with local recurrence (P = .01). In addition, the patients older than 57 years, lesions with bone involvement, the high-grade tumors and the cases with a history of recurrence and metastasis were associated with a lower overall survival (P < .05). Conclusion: By assembling all eligible cases in the literature, the present systematic review determined the most common clinicopathological profile of acinic cell carcinoma and the most relevant prognostic factors in a distinctly representative sample. The survey demonstrated the importance of considering the histopathological grading in order to better define the treatment for each case.pt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofJournal of oral pathology & medicinept_BR
dc.rightsAcesso Restritopt_BR
dc.subjectNeoplasia de glândula salivarpt_BR
dc.subject11acesso restrito assunto: Mouth NeoplasmsClinicopathological analysis of oral and maxillofacial acinic cell carcinoma: a systematic review nome periódico Journal of oral pathology & medicine busca dia 11/12/2023 fao clínica assuntopt_BR
dc.subject.otherCarcinoma, Acinar cellpt_BR
dc.subject.otherMouth neoplasmspt_BR
dc.subject.otherPrognosispt_BR
dc.subject.otherParotid glandpt_BR
dc.subject.otherRecurrencept_BR
dc.subject.otherNeoplasm metastasispt_BR
dc.titleClinicopathological analysis of oral and maxillofacial Acinic cell carcinoma: a systematic reviewpt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://onlinelibrary.wiley.com/doi/10.1111/jop.13159pt_BR
dc.identifier.orcidspt_BR
Appears in Collections:Artigo de Periódico

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