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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/67584
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dc.creatorÉrica Azevedo Costapt_BR
dc.creatorDanielle Freitas Henriquespt_BR
dc.creatorDaniele Barbosa de Almeida Medeirospt_BR
dc.creatorMaria Isabel Maldonado Coelho Guedespt_BR
dc.creatorBeatriz Senra Álvares da Silva Santospt_BR
dc.creatorAila Solimar Gonçalves Silvapt_BR
dc.creatorRenata de Pino Albuquerque Maranhãopt_BR
dc.creatorNieli Rodrigues da Costa Fariapt_BR
dc.creatorRenata Farinelli de Siqueirapt_BR
dc.creatorTulio de Oliveirapt_BR
dc.creatorKarina Ribeiro Leite Jardim Cavalcantept_BR
dc.creatorMarta Giovanettipt_BR
dc.creatorNoely Fabiana Oliveira de Mourapt_BR
dc.creatorAlessandro Pecego Martins Romanopt_BR
dc.creatorCarlos F. Campelo de Albuquerquept_BR
dc.creatorLauro César Soares Feitosapt_BR
dc.creatorJosé Joffre Martins Bayeuxpt_BR
dc.creatorRaffaella Bertoni Cavalcanti Teixeirapt_BR
dc.creatorOsmaikon Lisboa Lobatopt_BR
dc.creatorSilvokleio da Costa Silvapt_BR
dc.creatorAna Maria Bispo de Filippispt_BR
dc.creatorRivaldo Venâncio da Cunhapt_BR
dc.creatorLilian Silva Catenaccipt_BR
dc.creatorJosé Lourençopt_BR
dc.creatorLuiz Carlos Junior Alcantarapt_BR
dc.creatorVagner Fonsecapt_BR
dc.creatorFlávia Figueira Aburjailept_BR
dc.creatorFlávia l. l. Chalhoubpt_BR
dc.creatorJoilson Xavierpt_BR
dc.creatorFelipe Campos de Melo Ianipt_BR
dc.creatorMarcelo Adriano da Cunha e Silva Vieirapt_BR
dc.date.accessioned2024-04-23T14:39:50Z-
dc.date.available2024-04-23T14:39:50Z-
dc.date.issued2021-07-15-
dc.citation.volume10pt_BR
dc.citation.issue7pt_BR
dc.citation.spage896pt_BR
dc.citation.epage14pt_BR
dc.identifier.doihttps://doi.org/10.3390/pathogens10070896pt_BR
dc.identifier.issn2076-0817pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/67584-
dc.description.resumoBackground: West Nile virus (WNV) was first sequenced in Brazil in 2019, when it was isolated from a horse in the Espírito Santo state. Despite multiple studies reporting serological evidence suggestive of past circulation since 2004, WNV remains a low priority for surveillance and public health, such that much is still unknown about its genomic diversity, evolution, and transmission in the country. Methods: A combination of diagnostic assays, nanopore sequencing, phylogenetic inference, and epidemiological modeling are here used to provide a holistic overview of what is known about WNV in Brazil. Results: We report new genetic evidence of WNV circulation in southern (Minas Gerais, São Paulo) and northeastern (Piauí) states isolated from equine red blood cells. A novel, climate-informed theoretical perspective of the potential transmission of WNV across the country highlights the state of Piauí as particularly relevant for WNV epidemiology in Brazil, although it does not reject possible circulation in other states. Conclusion: Our output demonstrates the scarceness of existing data, and that although there is sufficient evidence for the circulation and persistence of the virus, much is still unknown on its local evolution, epidemiology, and activity. We advocate for a shift to active surveillance, to ensure adequate preparedness for future epidemics with spill-over potential to humans.pt_BR
dc.description.sponsorshipOutra Agênciapt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentVET - DEPARTAMENTO DE CLÍNICA E CIRURGIApt_BR
dc.publisher.departmentVET - DEPARTAMENTO DE MEDICINA VETERINÁRIA PREVENTIVApt_BR
dc.publisher.departmentVETER - ESCOLA DE VETERINARIApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofPathogenspt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectWest Nile viruspt_BR
dc.subjectGenomic monitoringpt_BR
dc.subjectMolecular detectionpt_BR
dc.subjectBrazilpt_BR
dc.subject.otherVírus do Nilo Ocidentalpt_BR
dc.subject.otherGenomapt_BR
dc.subject.otherMoléculaspt_BR
dc.subject.otherBrasilpt_BR
dc.titleWest Nile Virus in Brazilpt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.mdpi.com/2076-0817/10/7/896pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-5521-6448pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-3916-2018pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-5849-7326pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-2257-7076pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-1067-1882pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-3629-8529pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-6734-0216pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-1497-4397pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-3731-3660pt_BR
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