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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/68073
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dc.creatorJulya Ribeiro Campospt_BR
dc.creatorCarolina de Castro Martinspt_BR
dc.creatorSandro Felipe Santos Fariapt_BR
dc.creatorAna Paula Carvalhopt_BR
dc.creatorAlexandre Godinho Pereirapt_BR
dc.creatorFernando Oliveira Costapt_BR
dc.creatorLuís Otávio Miranda Cotapt_BR
dc.date.accessioned2024-05-03T19:43:05Z-
dc.date.available2024-05-03T19:43:05Z-
dc.date.issued2022-06-
dc.citation.volume26pt_BR
dc.citation.spage5557pt_BR
dc.citation.epage5574pt_BR
dc.identifier.doihttps://doi.org/10.1007/s00784-022-04583-xpt_BR
dc.identifier.issn1436-3771pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/68073-
dc.description.resumoObjectives: To evaluate the role of metabolic syndrome (MetS) components in the association with periodontitis (PE) (#CRD42020218310). Materials and methods: A systematic electronic search was performed in PUBMED, Scielo and Lilacs databases up to April 2022. Cross-sectional, case–control, and cohort studies presenting data on the association between MetS and PE in the adult and elderly populations were included. A random effect meta-analysis was performed to determine association effect estimates. Results interpretation followed the assessment of methodological quality (Joana Briggs Institute tool) together with the certainty of evidence (GRADE approach). Results: This review included 52 studies, totalling 140,434 participants, and 38 studies were meta-analyzed. Association between PE and MetS was observed (ORadj from 1.27 to 1.90; PRajd = 1.19; RRadj from 1.10 to 1.37) (low and very low certainty of evidence). Hyperglycaemia (OR = 1.18), HDL (OR = 1.16), obesity (OR = 1.08), and hypertension (OR = 1.11) were associated with PE, except triglycerides (low and very low certainty of evidence). There was a dose–response gradient between the number of MetS components and PE, with a gradual increase in the effect magnitude for 1 (OR = 1.14), 2 (OR = 1.52), 3 or more (OR = 1.79), and 4 or 5 components (OR = 2.02) (low to high certainty of evidence). Conclusions: MetS was associated with PE, with a dose–response gradient between the number of MetS components and the occurrence of PE, with an increasing effect magnitude according to an increasing number of components. Clinical relevance: Periodontal examination should be part of a comprehensive propaedeutic approach of MetS patients, particularly those presenting a great number of components.pt_BR
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológicopt_BR
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAO - DEPARTAMENTO DE ODONTOPEDIATRIA E ORTODONTIApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofClinical Oral Investigations-
dc.rightsAcesso Restritopt_BR
dc.subjectHyperglycemiapt_BR
dc.subjectHypertensionpt_BR
dc.subjectMetabolic syndromept_BR
dc.subjectObesitypt_BR
dc.subjectPeriodontal diseasespt_BR
dc.subjectPeriodontitispt_BR
dc.subject.otherHyperglycemiapt_BR
dc.subject.otherHypertensionpt_BR
dc.subject.otherMetabolic syndromept_BR
dc.subject.otherObesitypt_BR
dc.subject.otherPeriodontal diseasespt_BR
dc.subject.otherPeriodontitispt_BR
dc.titleAssociation between components of metabolic syndrome and periodontitis: a systematic review and meta‑analysispt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://link.springer.com/article/10.1007/s00784-022-04583-xpt_BR
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