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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/69135
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dc.creatorJosé Roberto Cortellipt_BR
dc.creatorSheila Cavalca Cortellipt_BR
dc.creatorDavi Romeiro Aquinopt_BR
dc.creatorTaís Browne Mirandapt_BR
dc.creatorJoão Carlos Moreira Jardimpt_BR
dc.creatorFernando de Oliveira Costapt_BR
dc.date.accessioned2024-06-11T20:05:23Z-
dc.date.available2024-06-11T20:05:23Z-
dc.date.issued2020-08-
dc.citation.volume116pt_BR
dc.citation.spage104747pt_BR
dc.citation.epageXpt_BR
dc.identifier.doihttps://doi.org/10.1016/j.archoralbio.2020.104747pt_BR
dc.identifier.issn00039969pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/69135-
dc.description.resumoObjective: This 6-year study evaluatedAggregatibacter actinomycetemcomitans outcomes and their relationship to clinical status. Design: From the eligible individuals (23-70 years of age), 31 regular compliers (between-visit interval < 6 months) were randomly selected and matched for age/sex with 31 irregular compliers (between-visit interval > 6 months). Periodontal clinical examination and subgingival samples were obtained 5 times: T1 (baseline), T2 (after active periodontal therapy), T3 (2 years), T4 (4 years), and T5 (6 years). Total bacteria load, A. actinomycetemcomitans, and red complex species Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola levels were determined by qPCR while PCR was used to determine the occurrence of the a-b-c-d-e-f-g serotypes and the JP2 clone of A. actinomycetemcomitans. Data between groups was compared over time. Results: At baseline PCR revealed A. actinomycetemcomitans prevalence of 9.7 % and JP2 prevalence of 6.7 %. A. actinomycetemcomitans qPCR levels were higher among individuals < 35 years of age and increased at T2 in irregular compliers. At in irregular compliers at the three follow-up visits. Serotypes a, d, and f showed greater values in at least one follow-up visit in regular compliers. A. actinomycetemcomitans showed negative correlation with probing depth (PD) while serotype b showed negative correlations with PD, PI, clinical attachment level and red complex. Conclusions: Longitudinally, compliance during PMT contributed to lower A. actinomycetemcomitans levels with some degree of correlation with clinical status. However, this study failed to report any positive effect on the occurrence of the most virulent representatives, i.e. serotype b and the JP2 clone.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofArchives of Oral Biologypt_BR
dc.rightsAcesso Restritopt_BR
dc.subjectAggregatibacter actinomycetemcomitanspt_BR
dc.subjectserotypes acesso restrito título periódico:Archives of Oral Biology busca dia 27/05/2024 mês maio ano d.c depois de Cristo.assunto Aggregatibacter actinomycetemcomitans. fao clínica. Aggregatibacter actinomycetemcomitans serotypes and jp2 outcomes related to clinical status over 6 years under periodontal maintenance therapypt_BR
dc.subjectJP2 clone of Aggregatibacter actinomyctemcomitanspt_BR
dc.subjectPeriodontal Maintenance Therapypt_BR
dc.subject.otherAggregatibacter actinomycetemcomitanspt_BR
dc.subject.otherCompliancept_BR
dc.subject.otherExotoxinspt_BR
dc.subject.otherPorphyromonas gingivalispt_BR
dc.subject.otherLongitudinal studiespt_BR
dc.subject.otherTannerella forsythiapt_BR
dc.subject.otherTreponema denticolapt_BR
dc.subject.otherSerogrouppt_BR
dc.subject.otherTherapeuticspt_BR
dc.titleAggregatibacter actinomycetemcomitans serotypes and JP2 outcomes related to clinical status over 6 years under periodontal maintenance therapypt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.sciencedirect.com/science/article/pii/S0003996920301254?via%3Dihubpt_BR
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