Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/69187
Type: Artigo de Periódico
Title: Artificial urinary sphincter for urinary incontinence after radical prostatectomy: a historical cohort from 2004 to 2015
Authors: Augusto Cesar Soares dos Santos Junior
Luíza de Oliveira Rodrigues
Daniela Castelo Azevedo
Lélia Maria de Almeida Carvalho
Mariana Ribeiro Fernandes
Sandra de Oliveira Sapori Avelar
Maria da Glória Cruvinel Horta
Silvana Márcia Bruschi Kelles
Abstract: This study aimed to retrospectively evaluate a cohort of patients with prostate cancer and persistent urinary incontinence after radical prostatectomy. From January 2004 to December 2015, eighty-six individuals were identified to have received an AUS implant, provided by a private nonprofit HMO operating in Belo Horizonte, Brazil. On total, there were 91 AUS implants, with a median interval between radical prostatectomy and AUS implant of 3.6 years (IQR 1.9 to 5.5). The rate of AUS cumulative survival, after a median follow-up of 4.1 years (IQR 1.7-7.2 years), was 44% (n=40). The median survival of AUS implants was 2.9 years (IQR 0.5-7.9 years). Thirty-seven AUS implants (40.7%) resulted in grade III surgical complications. There were 5 deaths at 2.1, 4.7, 5.7, 5.7 and 6.5 years of follow-up, but none due to causes directly associated to the AUS implant. Persistent severe incontinence was documented in 14 (15.3%) additional patients. From the 51 AUS implants which resulted in grade III surgical complications or persistent severe incontinence, 24 (47.1%) underwent surgical revisions. Explantation of the sphincter or its components was observed in 6 cases (25.0%). Mechanical failure, described as fluid loss and/or inability to recycle the AUS device, was observed in 4 devices (16.7%). In conclusion, although AUS implants are recommended as the gold-standard treatment of severe urinary incontinence after prostatectomy, the observed high rates of malfunction and grade III adverse events are a matter of concern warranting further assessment on the safety and efficacy of these devices.
Subject: Neoplasias da Próstata
Neoplasias
Prostatectomia
Incontinência Urinária
language: eng
metadata.dc.publisher.country: Brasil
Publisher: Universidade Federal de Minas Gerais
Publisher Initials: UFMG
metadata.dc.publisher.department: MEDICINA - FACULDADE DE MEDICINA
Rights: Acesso Aberto
metadata.dc.identifier.doi: https://doi.org/10.1590/S1677-5538.IBJU.2016.0244
URI: http://hdl.handle.net/1843/69187
Issue Date: 2017
metadata.dc.url.externa: https://www.scielo.br/j/ibju/a/dbQcBJZ99QbBLg3pV9XRXHh/?lang=en
metadata.dc.relation.ispartof: International Brazilian Journal of Urology
Appears in Collections:Artigo de Periódico



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