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http://hdl.handle.net/1843/69438| Type: | Artigo de Periódico |
| Title: | Association between liver cirrhosis and peri-implant diseases: a case-control study on implant- and patient-related risk factors |
| Authors: | Fernando de Oliveira Costa Sheila Cavalca Cortelli José Roberto Cortelli Eugênio José Pereira Lages Gustavo Henrique Mattos Pereira Adriana Moreira Costa Luís Otávio Miranda Cota |
| Abstract: | Objective: The objective of this study was to evaluate the potential association between liver cirrhosis and peri-implant diseases, as well as the influence of different risk indicators on this association. Methods: This case-control study included 64 cases with liver cirrhosis and 128 controls without liver diseases that presented the same socio-demographic and economic profile. The specific inclusion criteria were the following: aged group of 35-55 years and presenting at least one osseointegrated implant functioning for >5 years. A full-mouth peri-implant and periodontal examination was performed and risk variables were recorded. The association between risk variables and the occurrence of peri-implant diseases was tested through univariate analysis and multivariate logistic regression, stratified by alcohol status. Additionally, a mediation analysis was performed to examine the mediating effect of age with peri-implantitis. Results: A high prevalence of peri-implantitis (29.7%) was observed among cases when compared to controls (18.0%). Individuals with cirrhosis presented ~2.5 higher chance of having peri-implantitis than controls (p<0.001). Significant variables associated with the occurrence of peri-implantitis in the final logistic model were the following: cirrhosis, alcohol use, age (>55 years), male sex, smoking, periodontitis, and number of ≤14. Conclusions: An important risk association between liver cirrhosis and peri-implantitis was reported. Future studies with a larger sample size controlling for the patient- and implant-related confounders are needed to better understand the link between peri-implantitis and liver cirrhosis. Clinical relevance: Cirrhosis individuals, age, and periodontitis, as well as alcohol use and smoking interaction, should be considered as potential risk indicators for peri-implantitis. |
| Subject: | Case-control studies Liver cirrhosis Risk factors Dental implantation, endosseous Age groups Ethanol Periodontitis Tobacco use disorder |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | FAO - DEPARTAMENTO DE CLÍNICA |
| Rights: | Acesso Restrito |
| metadata.dc.identifier.doi: | https://doi.org/10.1007/s00784-021-04324-6 |
| URI: | http://hdl.handle.net/1843/69438 |
| Issue Date: | 2-Dec-2021 |
| metadata.dc.url.externa: | https://link.springer.com/article/10.1007/s00784-021-04324-6 |
| metadata.dc.relation.ispartof: | Clinical Oral Investigations |
| Appears in Collections: | Artigo de Periódico |
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