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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/69716
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dc.creatorBernardo Carvalho Dutrapt_BR
dc.creatorAlcione Maria Soares Dutra de Oliveirapt_BR
dc.creatorPeterson Antonio Dutra de Oliveirapt_BR
dc.creatorLuis Otávio de Miranda Cotapt_BR
dc.creatorFernando de Oliveira Costapt_BR
dc.date.accessioned2024-07-04T17:55:55Z-
dc.date.available2024-07-04T17:55:55Z-
dc.date.issued2022-04-
dc.citation.volume24pt_BR
dc.citation.issue2pt_BR
dc.citation.spage149pt_BR
dc.citation.epage157pt_BR
dc.identifier.issn2518-3745pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/69716-
dc.description.resumoAim: The primary aim of this randomized split-mouth triple-blind placebo-controlled clinical trial was to assess, by means of cone-beam computed tomography (CBCT), the effect of surgical topical use of 1%- Sodium alendronate (ALN) on the reduction of periodontal intrabony defects. Material and methods: Sixty-four intrabony defects from 32 patients with periodontitis were randomly treated with either 1%-ALN gel or placebo gel during periodontal surgeries. Periodontal clinical parameters were recorded at baseline and at 90 (T1) and 180 days (T2) after surgical treatment. Bone defects were evaluated by digital subtraction radiography (DSR) and CBCT at baseline and T2. Results: At T2, intergroup analysis showed significantly better periodontal clinical parameters, higher positive effects on periodontal bone repair (p<0.001) detected through DSR and greater bone filling detected through CBCT (p<0.001) for the ALN group. Moreover, the sensitivity of DSR in relation to CBCT increases with higher bone filling gain, i.e., small filling gains (≤0.5-to-<1.0 mm) are not detected by DSR. Conclusions: Topical application of 1%-ALN gel in intrabony defects showed better clinical results and significantly greater bone filling detected through CBCT compared to a placebo gel after 6 months.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofThe Journal of International Academy of Periodontologypt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectCONE BEAM COMPUTED TOMOGRAPHYpt_BR
dc.subjectradiographiespt_BR
dc.subjectaleandronate open acess busca dia 03/07/2024 fao clínica assunto Alendronate'cone-beam computed tomography analysis of the effects of topical application of 1% sodium alendronate gel in the surgical treatment of periodontal intrabony defects: a 6-month human randomized controlled clinical trial'pt_BR
dc.subjectPeriodontitis open acess busca dia 03/07/2024 fao clínica assunto Alendronate'cone-beam computed tomography analysis of the effects of topical application of 1% sodium alendronate gel in the surgical treatment of periodontal intrabony defects: a 6-month human randomized controlled clinical trial'pt_BR
dc.subjectClinical trialspt_BR
dc.subjectThe Journal of International Academy of Periodontology periódicopt_BR
dc.subject.otherEvaluation studypt_BR
dc.subject.otherAlendronatept_BR
dc.subject.otherPeriodontitispt_BR
dc.subject.otherCone-beam computed tomographypt_BR
dc.subject.otherRadiographypt_BR
dc.titleCone-beam computed tomography analysis of the effects of topical application of 1% sodium alendronate gel in the surgical treatment of periodontal intrabony defects: a 6-month human randomized controlled clinical trialpt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.perioiap.org/publications/60-april-2022/270-cone-beam-computed-tomography-analysis-of-the-effects-of-topical-application-of-1-sodium-alendronate-gel-in-the-surgical-treatment-of-periodontal-intrabony-defects-a-6-month-human-randomized-controlled-clinical-trialpt_BR
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