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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/69771
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dc.creatorPaula Luize Camargos Fonsecapt_BR
dc.creatorHelena P. Coelhopt_BR
dc.creatorAlana V. B. Costapt_BR
dc.creatorWalyson C. Costapt_BR
dc.creatorAlex F. de Carvalhopt_BR
dc.creatorBruna W. F. de Fariapt_BR
dc.creatorAline Brito de Limapt_BR
dc.creatorEneida Santos de Oliveirapt_BR
dc.creatorCarolina Senra Alves de Souzapt_BR
dc.creatorFernanda Gil de Souzapt_BR
dc.creatorRillery C. Diaspt_BR
dc.creatorFilipe R. R. Moreirapt_BR
dc.creatorVictor E. V. Geddespt_BR
dc.creatorIgor P. Godinhopt_BR
dc.creatorAlessandro L. Gonçalvespt_BR
dc.creatorKarine Lima Lourençopt_BR
dc.creatorRubens D. M. Magalhãespt_BR
dc.creatorFrederico Scott Varella Maltapt_BR
dc.creatorEva L. A. Medeirospt_BR
dc.creatorFernanda Santos Mendespt_BR
dc.creatorPedro H. B. de P. Mendespt_BR
dc.creatorCristiane P. T. B. Mendonçapt_BR
dc.creatorRafael M. de Souzapt_BR
dc.creatorAndre L. Menezespt_BR
dc.creatorDiego Menezespt_BR
dc.creatorMariane Talon de Menezespt_BR
dc.creatorLucyene Miguita Luizpt_BR
dc.creatorRennan G. Moreirapt_BR
dc.creatorRenata B. Peixotopt_BR
dc.creatorDaniel Costa Queirozpt_BR
dc.creatorAdriana A. Ribeiropt_BR
dc.creatorAna Paula de B. Ribeiropt_BR
dc.creatorJuliana Wilke Salibapt_BR
dc.creatorNatalia Rocha Guimarãespt_BR
dc.creatorHugo I. Satopt_BR
dc.creatorJoice do P. Silvapt_BR
dc.creatorNatiely Pereira Silvapt_BR
dc.creatorNuno R. Fariapt_BR
dc.creatorSantuza Maria Ribeiro Teixeirapt_BR
dc.creatorFlávio Guimarães da Fonsecapt_BR
dc.creatorAna Paula Salles Moura Fernandespt_BR
dc.creatorDanielle Alves Gomes Zaulipt_BR
dc.creatorJosé Nélio Januariopt_BR
dc.creatorJaqueline Silva de Oliveirapt_BR
dc.creatorNara de Oliveira Carvalhopt_BR
dc.creatorFelipe Campos de Melo Ianipt_BR
dc.creatorRenato Santana de Aguiarpt_BR
dc.creatorRenan Pedra de Souzapt_BR
dc.creatorTalita Émile Ribeiro Adelinopt_BR
dc.creatorHugo José Alvespt_BR
dc.creatorLuige Biciati Alvimpt_BR
dc.creatorDarlan S. Candidopt_BR
dc.date.accessioned2024-07-05T20:53:19Z-
dc.date.available2024-07-05T20:53:19Z-
dc.date.issued2022-
dc.citation.volume8pt_BR
dc.citation.issue2pt_BR
dc.citation.spage1pt_BR
dc.citation.epage16pt_BR
dc.identifier.doi10.1093/ve/veac064pt_BR
dc.identifier.issn2057-1577pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/69771-
dc.description.resumoThe emergence and global dissemination of Severe Acute Respiratory Syndrome virus 2 (SARS-CoV-2) variants of concern (VOCs) have been described as the main factor driving the Coronavirus Disease 2019 pandemic. In Brazil, the Gamma variant dominated the epidemiological scenario during the first period of 2021. Many Brazilian regions detected the Delta variant after its first description and documented its spread. To monitor the introduction and spread of VOC Delta, we performed Polymerase Chain Reaction (PCR) genotyping and genome sequencing in ten regional sentinel units from June to October 2021 in the State of Minas Gerais (MG). We documented the introduction and spread of Delta, comprising 70 per cent of the cases 8 weeks later. Comparing the viral loads of the Gamma and Delta dominance periods, we provide additional evidence that the latter is more transmissible. The spread and dominance of Delta did not culminate in the increase in cases and deaths, suggesting that the vaccination may have restrained the epidemic growth. Analysis of 224 novel Delta genomes revealed that Rio de Janeiro state was the primary source for disseminating this variant in the state of MG. We present the establishment of Delta, providing evidence of its enhanced transmissibility and showing that this variant shift did not aggravate the epidemiological scenario in a high immunity setting.pt_BR
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológicopt_BR
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Geraispt_BR
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorpt_BR
dc.description.sponsorshipFINEP - Financiadora de Estudos e Projetos, Financiadora de Estudos e Projetospt_BR
dc.description.sponsorshipFAPERJ - Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiropt_BR
dc.description.sponsorshipFAPESP - Fundação de Amparo à Pesquisa do Estado de São Paulopt_BR
dc.format.mimetypepdfpt_BR
dc.languageporpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFAR - DEPARTAMENTO DE ANÁLISES CLÍNICAS E TOXICOLÓGICASpt_BR
dc.publisher.departmentICB - DEPARTAMENTO DE BIOQUÍMICA E IMUNOLOGIApt_BR
dc.publisher.departmentICB - DEPARTAMENTO DE MICROBIOLOGIApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofVirus Evolutionpt_BR
dc.rightsAcesso Abertopt_BR
dc.subject.otherFilogeniapt_BR
dc.subject.otherFilogeografiapt_BR
dc.subject.otherVacinas contra COVID-19pt_BR
dc.subject.otherVacinaçãopt_BR
dc.subject.otherSARS-CoV-2pt_BR
dc.titleTracking the turnover of SARS-CoV-2 VOCs Gamma to Delta in a Brazilian state (Minas Gerais) with a high-vaccination statuspt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://academic.oup.com/ve/article/8/2/veac064/6650740?login=truept_BR
Appears in Collections:Artigo de Periódico

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