Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/70472
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dc.creatorMariana Raquel Soares Guillenpt_BR
dc.creatorEline Lima Borgespt_BR
dc.creatorGilmara Lopes Amorimpt_BR
dc.creatorPuebla Cassini Vieirapt_BR
dc.creatorAntonio Carlos Martins Guedespt_BR
dc.creatorLucíola da Silva Barcelospt_BR
dc.date.accessioned2024-07-12T20:02:56Z-
dc.date.available2024-07-12T20:02:56Z-
dc.date.issued2022-
dc.citation.volume37pt_BR
dc.citation.issue12pt_BR
dc.citation.spage1pt_BR
dc.citation.epage14pt_BR
dc.identifier.doi10.1590/acb371206pt_BR
dc.identifier.issn16782674pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/70472-
dc.description.resumoPurpose: To analyze the in昀氀uence of occlusive dressing on the healing of excisional skin wounds in mice. Methods: Pre-clinical, comparative, and translational study. Mice were divided into three experimental groups: wounds occluded with hydrocolloid (HD) dressings, transparent polyurethane 昀椀lm (TF) dressings, and without occlusion (WO), monitored at three, six and 14 days, with eight animals each. Closure rate, in昀椀ltration of neutrophils and macrophages, measurement of tumor necrosis factor-α (TNF-α) and vascular endothelial growth factor (VEGF) and, histologically, angiogenesis were evaluated. Results: Wound closure was accelerated in the occlusive groups. There was a decrease in TNF-α levels in the HD group when compared to the WO and TF groups. Neutrophils accumulation decreased in the HD group. Increased dosages of macrophages were evidenced in the HD group, compared to the WO and TF groups. Levels of VEGF were increased in the TF and HD groups. Conclusion: It is suggested that the occlusion of wounds modulates the in昀氀ammatory response.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentENF - DEPARTAMENTO DE ENFERMAGEM BÁSICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofActa Cirúrgica Brasileira-
dc.rightsAcesso Abertopt_BR
dc.subjectWounds and Injuriespt_BR
dc.subjectWound Healingpt_BR
dc.subjectOcclusive Dressingspt_BR
dc.subjectInflammationpt_BR
dc.subject.otherWounds and Injuriespt_BR
dc.subject.otherOcclusive Dressingspt_BR
dc.subject.otherDescritor em espanhol:pt_BR
dc.subject.otherInflammationpt_BR
dc.titleThe use of occlusive dressings: influence on excisional wound healing in animal modelpt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://doi.org/10.1590/acb371206pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-1220-6041pt_BR
Appears in Collections:Artigo de Periódico

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