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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/70478
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dc.creatorJosé Fábio Lanapt_BR
dc.creatorMarco Antônio Percope de Andradept_BR
dc.creatorLucas Furtado da Fonsecapt_BR
dc.creatorGabriel Azzinipt_BR
dc.creatorGabriel Santospt_BR
dc.creatorMarcelo Bragapt_BR
dc.creatorAlvaro Motta Cardoso Juniorpt_BR
dc.creatorWilliam D. Murrellpt_BR
dc.creatorAlberto Gobbipt_BR
dc.creatorJoseph Puritapt_BR
dc.date.accessioned2024-07-12T20:17:22Z-
dc.date.available2024-07-12T20:17:22Z-
dc.date.issued2021-03-09-
dc.citation.volume22pt_BR
dc.citation.issue5pt_BR
dc.citation.spage1pt_BR
dc.citation.epage12pt_BR
dc.identifier.doi10.3390/ijms22052762pt_BR
dc.identifier.issn1422-0067pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/70478-
dc.description.resumoThe rise in musculoskeletal disorders has prompted medical experts to devise novel effective alternatives to treat complicated orthopedic conditions. The ever-expanding field of regenerative medicine has allowed researchers to appreciate the therapeutic value of bone marrow-derived biological products, such as the bone marrow aspirate (BMA) clot, a potent orthobiologic which has often been dismissed and regarded as a technical complication. Numerous in vitro and in vivo studies have contributed to the expansion of medical knowledge, revealing optimistic results concerning the application of autologous bone marrow towards various impactful disorders. The bone marrow accommodates a diverse family of cell populations and a rich secretome; therefore, autologous BMA-derived products such as the “BMA Matrix”, may represent a safe and viable approach, able to reduce the costs and some drawbacks linked to the expansion of bone marrow. BMA provides —it eliminates many hurdles associated with its preparation, especially in regards to regulatory compliance. The BMA Matrix represents a suitable alternative, indicated for the enhancement of tissue repair mechanisms by modulating inflammation and acting as a natural biological scaffold as well as a reservoir of cytokines and growth factors that support cell activity. Although promising, more clinical studies are warranted in order to further clarify the efficacy of this strategy.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE APARELHO LOCOMOTORpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofInternational Journal of Molecular Sciencespt_BR
dc.rightsAcesso Abertopt_BR
dc.subject.otherMedicina Regenerativapt_BR
dc.subject.otherÁcido Hialurônicopt_BR
dc.subject.otherCicatrizaçãopt_BR
dc.subject.otherDoenças Musculoesqueléticaspt_BR
dc.subject.otherMedula Ósseapt_BR
dc.titleBone marrow aspirate matrix: a convenient ally in regenerative medicinept_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.mdpi.com/1422-0067/22/5/2762pt_BR
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