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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/70612
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dc.creatorRafael da Rocha Macedopt_BR
dc.creatorLucas Furtado da Fonsecapt_BR
dc.creatorJosé Fábio Santos Duarte Lanapt_BR
dc.creatorTomas Mosanerpt_BR
dc.creatorJoseph Puritapt_BR
dc.creatorMarco Antônio Percope de Andradept_BR
dc.creatorLuciano Miller Rodriguespt_BR
dc.creatorPatricio Centurionpt_BR
dc.date.accessioned2024-07-15T20:10:56Z-
dc.date.available2024-07-15T20:10:56Z-
dc.date.issued2021-02-28-
dc.citation.volume9pt_BR
dc.citation.issue1pt_BR
dc.citation.spage29pt_BR
dc.citation.epage39pt_BR
dc.identifier.doi10.13105/wjma.v9.i1.29pt_BR
dc.identifier.issn2308-3840pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/70612-
dc.description.resumoAmong degenerative musculoskeletal disorders, osteoarthritis remains one of the main causes of pain and disability in the adult population. Current available alternatives to alleviate symptoms include conservative treatments such as physical therapy, anti-inflammatory drugs and an educational approach to lifestyle modification. The use of certain analgesics, such as opiates and corticosteroids offer short-term results but does not address the etiological source of pain and disability. In addition, prolonged use of such medications can cause additional complications. Therefore, the demand for regeneration of joint cartilage has led to an alternative approach called "orthobiologics". This alternative is based on cellular and molecular components capable of inducing and promoting tissue repair. Products derived from adipose tissue have been studied as an excellent source of orthobiologics in an attempt to promote joint cartilage repair. However, the lack of standardization regarding collection and processing protocols presents a challenge for the generalization of study results and determination of effectiveness. To the best of our knowledge, orthobiologics derived from fat have not yet been classified. Therefore, this manuscript proposes the HGS classification system which aims to describe certain parameters that are relevant to the quality of organic products regarding harvesting techniques (H), graft type (G), and number of centrifugations (S). The more parameters used would imply greater characterization and complexity of the evaluation of the biological product used. The HGS classification may provide a valuable contribution to the understanding of clinical procedures and research results, aiming to ultimately usher in a standardization of optimal practice.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentMED - DEPARTAMENTO DE APARELHO LOCOMOTORpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofWorld Journal of Meta-Analysispt_BR
dc.rightsAcesso Abertopt_BR
dc.subject.otherTecido Adiposopt_BR
dc.subject.otherCélulas-Tronco Mesenquimaispt_BR
dc.subject.otherMedicina Regenerativapt_BR
dc.subject.otherDoenças Musculoesqueléticaspt_BR
dc.subject.otherOrtopediapt_BR
dc.subject.otherOsteoartritept_BR
dc.titleBiofat grafts as an orthobiologic tool in osteoarthritis: an update and classification proposalpt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.wjgnet.com/2308-3840/full/v9/i1/29.htmpt_BR
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