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http://hdl.handle.net/1843/70761
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DC Field | Value | Language |
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dc.creator | Thais dos Santos Fontes Pereira | pt_BR |
dc.creator | Júlio Cesar Tanos de Lacerda | pt_BR |
dc.creator | Michelle Danielle Porto Matias | pt_BR |
dc.creator | Alessandro Oliveira de Jesus | pt_BR |
dc.creator | Ricardo Santiago Gomez | pt_BR |
dc.creator | Ricardo Alves Mesquita | pt_BR |
dc.date.accessioned | 2024-07-16T15:36:28Z | - |
dc.date.available | 2024-07-16T15:36:28Z | - |
dc.date.issued | 2016 | - |
dc.citation.volume | 8 | pt_BR |
dc.identifier.doi | https://doi.org/10.4317%2Fjced.52605 | pt_BR |
dc.identifier.issn | 1989-5488 | pt_BR |
dc.identifier.uri | http://hdl.handle.net/1843/70761 | - |
dc.description.abstract | O fibroblastoma desmoplásico é um tumor benigno de tecidos moles, de origem fibroblástica ou miofibroblástica, que raramente ocorre na cavidade oral. Relatamos o caso de um homem de 56 anos que apresentava tumor em rebordo alveolar mandibular esquerdo, de crescimento lento e assintomático, sem envolvimento ósseo. O tumor era séssil, com superfície lobulada, coberto por mucosa hígida com áreas eritematosas. A lesão foi excisada e os espécimes enviados para histopatologia e imuno-histoquímica. O exame histopatológico evidenciou proliferação fibroblástica não encapsulada, caracterizada por miofibroblastos, fibroblastos fusiformes e estrelados com núcleos grandes ou ovais e bi ou tri nucleação, imersos em abundante estroma hipocelular denso de colágeno. As células tumorais foram positivas para vimentina, HHF35, α-actina de músculo liso e fator XIIIa. O diagnóstico de fibroblastoma desmoplásico baseou-se na história clínica de ausência de trauma relacionado ao crescimento do rebordo alveolar, associado a características macroscópicas, microscópicas e imuno-histoquímicas. O paciente está livre de doenças há oito meses. | pt_BR |
dc.description.resumo | Desmoplastic fibroblastoma is benign soft tissue tumor, with fibroblastic or myofibroblastic origin, that rarely occurs in oral cavity. We reported the case of a 56-year-old man who presented a tumor in the left mandibular alveolar ridge, with slow and asymptomatic growth, with no osseous involvement. The tumor was sessile with lobulated surface, covered by healthy mucosa with erythematous areas. The lesion was excised and specimens sent to histopathology and immunohistochemistry. Histopathological exam showed a non-encapsulated fibroblastic proliferation, characterized by myofibroblasts, spindle and stellate fibroblasts with large or oval nuclei and bi or tri nucleation, immersed in an abundant hypocellular dense collagen stroma. Tumor cells were positive for vimentin, HHF35, α-smooth muscle actin and factor XIIIa. The diagnosis of desmoplastic fibroblastoma was based in the clinical history of absence of trauma related to the growth in the alveolar ridge, associated with macroscopic, microscopic and immunohistochemical features. The patient is free-diseases by eight months. | pt_BR |
dc.format.mimetype | pt_BR | |
dc.language | eng | pt_BR |
dc.publisher | Universidade Federal de Minas Gerais | pt_BR |
dc.publisher.country | Brasil | pt_BR |
dc.publisher.department | FAO - DEPARTAMENTO DE CLÍNICA | pt_BR |
dc.publisher.initials | UFMG | pt_BR |
dc.relation.ispartof | Journal of clinical and experimental dentistry | pt_BR |
dc.rights | Acesso Aberto | pt_BR |
dc.subject | Collagenous fibroma | pt_BR |
dc.subject | Desmoplastic fibroblastoma | pt_BR |
dc.subject | Neoplasm of connective and soft tissue | pt_BR |
dc.subject.other | Fibroma desmoplásico | pt_BR |
dc.subject.other | Boca | pt_BR |
dc.subject.other | Neoplasias de tecidos moles | pt_BR |
dc.title | Desmoplastic fibroblastoma (collagenous fibroma) of the oral cavity | pt_BR |
dc.type | Artigo de Periódico | pt_BR |
dc.url.externa | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4739375/ | pt_BR |
dc.identifier.orcid | https://orcid.org/0000-0002-5570-3550 | pt_BR |
dc.identifier.orcid | https://orcid.org/0000-0003-1858-1096 | pt_BR |
dc.identifier.orcid | https://orcid.org/0000-0001-8770-8009 | pt_BR |
Appears in Collections: | Artigo de Periódico |
Files in This Item:
File | Description | Size | Format | |
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Desmoplastic fibroblastoma (collagenous fibroma) of the oral cavity | 643.42 kB | Adobe PDF | View/Open |
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