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http://hdl.handle.net/1843/71085| Tipo: | Artigo de Periódico |
| Título: | Periodontal, microbiological and immunological clinical conditions in a 9-year-old child with localized advanced periodontitis: case reports in a 18-mouth follow-up |
| Autor(es): | Bruna Lara França Amanda Almeida Costa Luis Otávio de Miranda Cota Fernando de Oliveira Costa |
| Resumen: | Abstract : The objective of this study is to report a clinical case of a 9 year old child diagnosed with localized advanced and high risk periodontitis through periodontal clinical parameters and radiographic, microbiological and immunological exams. In the clinical examination was observed probing depth alteration of the four first molars, although there was no plaque compatible with the periodontal condition. Radiographic examination revealed angular bone loss in the mesial sites of elements 26, 36 and expressively of 16. Microbiological and immunological tests were performed from the collection of crevicular gingival fluid and saliva. Thus, total bacterial load count and specific bacterial levels of Aggregatibacter actinomycete mcomitans; Tannerella forsythia, Porphyromonas gingivalis; Treponema denticola; Prevotella intermedia and Actinomyces naeslundii were performed by qPCR (Polymerase Chain Reaction - real time), while levels of the biomarkers Interleukin 10 (IL-10), Interleukin 6 (IL-6), Interleukin beta (IL-β), Metaloproteinase of matrix-8 (MMP-8) and tumor necrosis factor alpha (TNF-α) by ELISA. The proposed treatment included non-surgical and surgical periodontal therapy and antimicrobial use. During the 18 month follow-up of the patient, the mechanical and chemical periodontal treatment promoted a significant improvement in all clinical and radiographic periodontal parameters and positively influenced the patient's bacterial and immunological profile. |
| Asunto: | Aggressive periodontitis Periodontitis Anti-bacterial agents Microbiology Immune system Bacteria Biomarkers Matrix metalloproteinase 8 Tumor necrosis factor-alpha Therapeutics Surgery, oral Bone resorption |
| Idioma: | eng |
| País: | Brasil |
| Editor: | Universidade Federal de Minas Gerais |
| Sigla da Institución: | UFMG |
| Departamento: | FAO - DEPARTAMENTO DE CLÍNICA |
| Tipo de acceso: | Acesso Aberto |
| Identificador DOI: | http://dx.doi.org/10.20431/2455-9806.040100 |
| URI: | http://hdl.handle.net/1843/71085 |
| Fecha del documento: | 2018 |
| metadata.dc.url.externa: | https://www.arcjournals.org/journal-of-clinical-case-reports/volume-4-issue-2/ |
| metadata.dc.relation.ispartof: | Arc Journal of Clinical Case Reports |
| Aparece en las colecciones: | Artigo de Periódico |
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| archivo | Descripción | Tamaño | Formato | |
|---|---|---|---|---|
| Periodontal, microbiological and immunological clinical conditions in a 9-year-old child with localized advanced periodontitis case reports in a 18-mouth follow-up.pdf | 2.15 MB | Adobe PDF | Visualizar/Abrir |
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