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http://hdl.handle.net/1843/71326| Type: | Artigo de Periódico |
| Title: | Mucosal leishmaniasis in brazilian patients: two case reports with similar clinical presentation and different approaches |
| Authors: | Aline Fernanda Cruz Renata Gonçalves Resende Daniel Ricaldoni Albuquerque Júlio César Tanos de Lacerda Camila Ferreira Leite Maria Cassia Ferreira de Aguiar |
| Abstract: | Mucosal leishmaniasis is a chronic infection that affects the upper respiratory tract and/or the oral mucosa caused by Leishmania protozoan parasites. We present two cases of oral leishmaniasis and discuss the different diagnostic strategies and treatment. In both cases, the patients were male, 60 and 94 years of age, and presented with lesions on the soft palate. In the first patient, the final diagnosis was made on the basis of histopathologic examination. In the second case, polymerase chain reaction and Montenegro skin test were necessary to confirm the diagnosis. The first patient was treated with meglumine antimoniate (Glucantime), and the lesions healed after 2 months. In the second case, the patient received treatment with liposomal amphotericin B but later died as a result of generalized infection. Mucosal leishmaniasis is a highly disfiguring disease. Early diagnosis is important to prevent a lethal outcome. |
| Subject: | Meglumine antimoniate Leishmaniasis Mouth mucosa Amphotericin B Therapeutics Diagnosis Leishmania |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | FAO - DEPARTAMENTO DE CLÍNICA |
| Rights: | Acesso Restrito |
| metadata.dc.identifier.doi: | https://doi.org/10.1016/j.oooo.2016.02.017 |
| URI: | http://hdl.handle.net/1843/71326 |
| Issue Date: | Dec-2016 |
| metadata.dc.url.externa: | https://www.sciencedirect.com/science/article/pii/S2212440316000882?via%3Dihub |
| metadata.dc.relation.ispartof: | Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology |
| Appears in Collections: | Artigo de Periódico |
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