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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/72257
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dc.creatorFlaviane Francisco Hiláriopt_BR
dc.creatorMohamed Dit Mady Traorépt_BR
dc.creatorVincent Zwickpt_BR
dc.creatorLaurence Berrypt_BR
dc.creatorCláudia Avello Simões Pirespt_BR
dc.creatorMuriel Cuendetpt_BR
dc.creatorNicolas Fantozzipt_BR
dc.creatorRossimiriam Pereira de Freitaspt_BR
dc.creatorMarjorie Maynadierpt_BR
dc.creatorSharon Weinpt_BR
dc.creatorHenri Vialpt_BR
dc.creatorYung-Sing Wongpt_BR
dc.date.accessioned2024-08-01T13:30:42Z-
dc.date.available2024-08-01T13:30:42Z-
dc.date.issued2017-
dc.citation.volume19pt_BR
dc.citation.issue3pt_BR
dc.citation.spage612pt_BR
dc.citation.epage615pt_BR
dc.identifier.doihttps://doi.org/10.1021/acs.orglett.6b03776pt_BR
dc.identifier.issn1523-7052pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/72257-
dc.description.resumoA small uncharged cyclopeptide scaffold inspired by a natural product and designed to undergo postfunctionalizations was used as a new transmembrane vector. A bioactive and fluorescent triazole aminocoumarin was bound to this carrier to facilitate its moving across cell and subcellular membranes, and this led to an increase in its cell toxicity.pt_BR
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológicopt_BR
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Geraispt_BR
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superiorpt_BR
dc.description.sponsorshipOutra Agênciapt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentICX - DEPARTAMENTO DE QUÍMICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofOrganic Letterspt_BR
dc.rightsAcesso Restritopt_BR
dc.subjectFluorescencept_BR
dc.subjectMembranespt_BR
dc.subjectPeptides and proteinspt_BR
dc.subjectPermeabilitypt_BR
dc.subjectTriazolept_BR
dc.subject.otherFluorescênciapt_BR
dc.subject.otherPeptídios - Síntesept_BR
dc.subject.otherTriazóispt_BR
dc.subject.otherTransporte biológicopt_BR
dc.titleSynthesis of an uncharged tetra-cyclopeptide acting as a transmembrane carrier: enhanced cellular and nuclear uptakept_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://pubs.acs.org/doi/10.1021/acs.orglett.6b03776pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-6974-3724pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-1038-9681pt_BR
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