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Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/72280
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dc.creatorDanielle de Souza Costapt_BR
dc.creatorAntoine Becharapt_BR
dc.creatorJonas Jardim de Paulapt_BR
dc.creatorMarco Aurélio Romano-Silvapt_BR
dc.creatorHumberto Corrêa da Silva Filhopt_BR
dc.creatorGuilherme Menezes Lagept_BR
dc.creatorDébora Marques de Mirandapt_BR
dc.creatorLeandro Fernandes Malloy-Dinizpt_BR
dc.date.accessioned2024-08-01T21:55:36Z-
dc.date.available2024-08-01T21:55:36Z-
dc.date.issued2016-
dc.citation.volume246pt_BR
dc.citation.spage650pt_BR
dc.citation.epage655pt_BR
dc.identifier.doi10.1016/j.psychres.2016.10.073pt_BR
dc.identifier.issn0165-1781pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/72280-
dc.description.resumoThe biological underpinnings of sex-related differences in decision-making are still under-explored. The COMT gene is related to sexual dimorphism and with different choices made under uncertainty, albeit no study has specifically investigated a moderation effect of sex on the association between the COMT gene and the performance on decision-making paradigms. In this study, we investigated the influence of the COMT Val158Met polymorphism on Iowa Gambling Task (IGT) performance depending on sex in a healthy adult sample. Participants were 192 healthy adults (84 men and 108 women). The first 40 choices in the IGT were considered decisions under ambiguity and the last 60 choices decisions under risk. To test our moderation hypothesis we used a separate regressions approach. The results revealed a sex-dependent effect of COMT Va l 158Met polymorphism on decision-making as measured by the IGT. Val/Val women showed the best performance in the last trials of the IGT. Therefore, the COMT Val158Met polymorphism may be considered a genetic marker underlying sex differences in decision-making.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentEEF - DEPARTAMENTO DE EDUCAÇÃO FÍSICApt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofPsychiatry Research-
dc.rightsAcesso Restritopt_BR
dc.subject.otherNeuropsicologiapt_BR
dc.subject.otherGenética molecularpt_BR
dc.subject.otherSexopt_BR
dc.titleInfluence of COMT Val158Met polymorphism on emotional decision-making: a sex-dependent relationship?pt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.sciencedirect.com/science/article/pii/S0165178116300312pt_BR
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