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http://hdl.handle.net/1843/74413| Type: | Artigo de Periódico |
| Title: | Survival analysis of recurrent squamous cell carcinoma of the lower oral cavity treated by surgery |
| Authors: | Alexandre de Andrade Sousa José Maria Porcaro Salles Patrícia Carlos Caldeira Karine Duarte da Silva Maria Cássia Ferreira Aguiar Diogo Melgaço Faria Gustavo de Moraes Jomar Carvalho Guilherme de Souza Silva João Marcos Soares |
| Abstract: | The aim of the present study was to investigate the survival of individuals with squamous cell carcinoma of the lower oral cavity who underwent surgical treatment and experienced recurrence, considering the site of the recurrent disease. A retrospective longitudinal study was conducted, comparing the survival rates of patients with and without recurrence and considering the site of recurrence (local, regional, distant). Statistical analysis was performed with SPSS and a p-value ≤ 0.05 was considered significant. The sample comprised 150 patients, 59 (39.3%) of whom experienced recurrence. Local recurrence occurred in 35 patients (23.4%), regional recurrence in 17 (11.3%), and distant recurrence in seven (4.6%). The average survival of participants with local, regional, and distant recurrence was 12, five, and two months, respectively. Patients with recurrent disease had worse survival than those who did not (P < 0.001). Patients with local recurrence had better survival than those with regional/distant recurrence (P = 0.011). All patients with regional and distant recurrence had deceased by the last follow-up. In conclusion, patients with local recurrence of squamous cell carcinoma of the lower oral cavity treated by surgery have a better survival rate than those with regional and distant recurrence. Local recurrence poses the possibility of curative salvage therapy. |
| Subject: | Mouth neoplasms Recurrence Salvage therapy Carcinoma, squamous cell Survival analysis Surgery, oral Survival rate |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | FAO - DEPARTAMENTO DE CLÍNICA |
| Rights: | Acesso Aberto |
| URI: | http://hdl.handle.net/1843/74413 |
| Issue Date: | 15-Jun-2021 |
| metadata.dc.url.externa: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8255197/ |
| metadata.dc.relation.ispartof: | International Journal of Clinical and Experimental Pathology |
| Appears in Collections: | Artigo de Periódico |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Survival analysis of recurrent squamous cell carcinoma of the lower oral cavity treated by surgery.pdf | 370.91 kB | Adobe PDF | View/Open |
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