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http://hdl.handle.net/1843/76846| Type: | Artigo de Periódico |
| Title: | Molecular details of ovalbumin solvation by an aqueous solution of xylitol in different pH environment: ultrasonic and molecular simulation studies |
| Authors: | K. Swenthira Kaique Mendes de Souza Laudelina Ferreira de Andrade Charles Martins Aguilar Caroline Honaiser Lescano Ivan Pires de Oliveira Veerappan Velusamy |
| Abstract: | Artificial sweetener-protein interactions are playing a major role in enhancing the functional properties of protein-based food and pharmaceutical products. This article discusses the molecular details of ovalbumin (OA) solvation in an aqueous solution of xylitol (XY) in different pH environments. This task can be accomplished by both Ultrasonic and Molecular Simulation studies. In ultrasonic studies, density, ultrasound velocity, viscosity, and surface tension have been measured for OA in various pH of phosphate buffer with and without XY. Further, some of the calculated parameters such as adiabatic compressibility, intermolecular free length, free volume, etc have been worked out. From ultrasonic results, pH dependent preferential hydration of OA was noticed in the presence of XY in an aqueous environment. In Molecular Dynamics Simulation (MDS) studies, water and XY accumulation to OA surface for different pH models were analyzed. The different states of protonation of the OA surface promote two distinct effects on the solvent and cosolvent orientation. |
| Subject: | Ovos -- Proteínas Xilitol Dinamica molecular Tensão superficial |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | ICA - INSTITUTO DE CIÊNCIAS AGRÁRIAS |
| Rights: | Acesso Restrito |
| metadata.dc.identifier.doi: | https://doi.org/10.1016/j.molliq.2023.122477 |
| URI: | http://hdl.handle.net/1843/76846 |
| Issue Date: | 2023 |
| metadata.dc.url.externa: | https://www.sciencedirect.com/science/article/pii/S0167732223012813 |
| metadata.dc.relation.ispartof: | Journal of Molecular Liquids |
| Appears in Collections: | Artigo de Periódico |
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