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http://hdl.handle.net/1843/77109| Tipo: | Artigo de Periódico |
| Título: | Histochemical analysis of collagen fibers in giant cell fibroma and inflammatory fibrous hyperplasia |
| Autor(es): | Mônica Jarema Schmidt Antonio Adilson Soares de Lima Teixeira Suelen Luiz Arielli Carine Michels Maria Cássia Ferreira Aguiar Aline Cristina Batista Rodrigues Johann André Tschoeke Lúcia Noronha Rafaela Scariot de Moraes Ricardo Alves de Mesquita Ana Maria Trindade Grégio Luciana Reis Azevedo Alanis Sérgio Aparecido Ignácio Jean Nunes dos Santos |
| Resumo: | Objective The aim was to investigate collagen fibers in giant cell fibroma, inflammatory fibrous hyperplasia, and oral normal mucosa. Materials and methods Sixty-six cases were stained with picrosirius red. The slides were observed under polarization, followed by the measurement of the area and the percentage of the type I and type III collagens. The age and gender were obtained from the clinical records. Results No differences could be observed in both the area and percentage of the type I and type III collagens within the categories of lesions and normal mucosa. In the giant cells fibroma, a greater area and percentage of type I collagen could be identified in individuals of less than 41.5 years (p < 0.05). Conclusion The distribution of type I and type III collagen fibers in the studied lesions followed a similar pattern to that observed in the normal mucosa, indicating a normal collagen maturation process of type III to I. The study supports that multinucleated and stellate cells of the giant cell fibroma appear to be functional within collagen types III and I turnover. The greater amount of type I collagen identified in giant cell fibroma in individuals of less than 41.5 years reinforce the neoplastic nature of lesion. |
| Assunto: | Fibroma Collagen Mouth mucosa Hyperplasia Neoplasms |
| Idioma: | eng |
| País: | Brasil |
| Editor: | Universidade Federal de Minas Gerais |
| Sigla da Instituição: | UFMG |
| Departamento: | FAO - DEPARTAMENTO DE CLÍNICA |
| Tipo de Acesso: | Acesso Restrito |
| Identificador DOI: | https://doi.org/10.1016/j.acthis.2016.04.007 |
| URI: | http://hdl.handle.net/1843/77109 |
| Data do documento: | Jun-2016 |
| metadata.dc.url.externa: | https://www.sciencedirect.com/science/article/pii/S0065128116300642#:~:text=The%20aim%20was%20to%20investigate%20collagen%20fibers%20in%20giant%20cell |
| metadata.dc.relation.ispartof: | Acta Histochemica |
| Aparece nas coleções: | Artigo de Periódico |
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