Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/77448
Type: Artigo de Periódico
Title: Oral bilateral collagenous fibroma: a previously unreported case and literature review
Authors: Ana Carolina Uchoa Vasconcelos
Ana Paula Neutzling Gomes
Sandra Beatriz Chaves Tarquinio
Eduardo Rodrigues Abduch
Ricardo Alves de Mesquita
Karine Duarte Silva
Abstract: Collagenous fibroma, also known as desmoplastic fibroblastoma, is a rare benign slow growing tumor particularly uncommon in the oral cavity. The aim of this study was to analyze the clinical and histopathological features of an oral collagenous fibroma as well as to compare this data with those reported in an English-literature review. The thirteenth case of collagenous fibroma in the oral cavity and the first to present clinically as a bilateral mass was described. A 48-years-old female patient was referred to a School of Dentistry, complaining about an asymptomatic swelling on the hard palate, lasting around ten years. The intraoral examination revealed two well-defined mass, bilaterally in the hard palate. An excisional biopsy was performed. Microscopically, the connective tissue consisted of dense collagen bundles in which were seen scarcely distributed spindle-shaped to stellate fibroblastic cells. Blood vessels were few, as well as inflammatory cells. Immunohistochemical staining was positive for vimentin, α-smooth muscle actin and factor XIIIa and negative for S-100, CD68, CD34, HHF35, desmin and AE1/AE3. The patient remains disease-free 24 months after excision. In conclusion, oral collagenous fibroma should be included in the differential diagnosis of bilateral sessile nodules in the oral cavity.
Subject: Connective tissue
Mouth diseases
Mouth neoplasms
Diagnosis, oral
Pathology, oral
Fibroma, desmoplastic
Palate, hard
Clinical study
Tissues
language: eng
metadata.dc.publisher.country: Brasil
Publisher: Universidade Federal de Minas Gerais
Publisher Initials: UFMG
metadata.dc.publisher.department: FAO - DEPARTAMENTO DE CLÍNICA
Rights: Acesso Aberto
metadata.dc.identifier.doi: https://doi.org/10.4317/jced.54123
URI: http://hdl.handle.net/1843/77448
Issue Date: 1-Jan-2018
metadata.dc.url.externa: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899808/
metadata.dc.relation.ispartof: Journal of Clinical and Experimental Dentistry
Appears in Collections:Artigo de Periódico

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