Please use this identifier to cite or link to this item:
http://hdl.handle.net/1843/77448
Type: | Artigo de Periódico |
Title: | Oral bilateral collagenous fibroma: a previously unreported case and literature review |
Authors: | Ana Carolina Uchoa Vasconcelos Ana Paula Neutzling Gomes Sandra Beatriz Chaves Tarquinio Eduardo Rodrigues Abduch Ricardo Alves de Mesquita Karine Duarte Silva |
Abstract: | Collagenous fibroma, also known as desmoplastic fibroblastoma, is a rare benign slow growing tumor particularly uncommon in the oral cavity. The aim of this study was to analyze the clinical and histopathological features of an oral collagenous fibroma as well as to compare this data with those reported in an English-literature review. The thirteenth case of collagenous fibroma in the oral cavity and the first to present clinically as a bilateral mass was described. A 48-years-old female patient was referred to a School of Dentistry, complaining about an asymptomatic swelling on the hard palate, lasting around ten years. The intraoral examination revealed two well-defined mass, bilaterally in the hard palate. An excisional biopsy was performed. Microscopically, the connective tissue consisted of dense collagen bundles in which were seen scarcely distributed spindle-shaped to stellate fibroblastic cells. Blood vessels were few, as well as inflammatory cells. Immunohistochemical staining was positive for vimentin, α-smooth muscle actin and factor XIIIa and negative for S-100, CD68, CD34, HHF35, desmin and AE1/AE3. The patient remains disease-free 24 months after excision. In conclusion, oral collagenous fibroma should be included in the differential diagnosis of bilateral sessile nodules in the oral cavity. |
Subject: | Connective tissue Mouth diseases Mouth neoplasms Diagnosis, oral Pathology, oral Fibroma, desmoplastic Palate, hard Clinical study Tissues |
language: | eng |
metadata.dc.publisher.country: | Brasil |
Publisher: | Universidade Federal de Minas Gerais |
Publisher Initials: | UFMG |
metadata.dc.publisher.department: | FAO - DEPARTAMENTO DE CLÍNICA |
Rights: | Acesso Aberto |
metadata.dc.identifier.doi: | https://doi.org/10.4317/jced.54123 |
URI: | http://hdl.handle.net/1843/77448 |
Issue Date: | 1-Jan-2018 |
metadata.dc.url.externa: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899808/ |
metadata.dc.relation.ispartof: | Journal of Clinical and Experimental Dentistry |
Appears in Collections: | Artigo de Periódico |
Files in This Item:
File | Description | Size | Format | |
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Oral bilateral collagenous fibroma a previously unreported case and literature review.pdf | 979.47 kB | Adobe PDF | View/Open |
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