Please use this identifier to cite or link to this item:
http://hdl.handle.net/1843/78180| Type: | Artigo de Periódico |
| Title: | Androgen receptor in salivary gland carcinoma: a review of an old marker as a possible new target |
| Authors: | Chit Cheng Yeoh Nedal Dabab Elyse Rigby Ritu Chhikara Iolia Akaev Ricardo Santiago Gomez Felipe Paiva Fonseca Peter Brennan Siavash Rahimi |
| Abstract: | The role of the androgen receptor (AR) as an immunomarker for diagnosis of salivary gland duct carcinoma (SDC) is well known. Other non-squamous cell head and neck cancers (NSCC-HN), including a small subset of salivary gland cancers (SGCs), can also express AR. With the increase in effective and powerful new generation of anti-androgen agents and drugs administered orally, more targetable AR-driven NSCC-HN, such as subsets of SGCs, should be investigated for possible expression of AR. In this review, we focus on SGC subtypes, which could express AR and describe the main androgen deprivation therapy (ADT) strategies. |
| Subject: | Abiraterone acetate Receptors, androgen Immunohistochemistry Carcinoma, mucoepidermoid Carcinoma, adenoid cystic Adenocarcinoma Prognosis Radiotherapy Excision repair Androgen antagonists Drug therapy |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | FAO - DEPARTAMENTO DE CLÍNICA |
| Rights: | Acesso Aberto |
| metadata.dc.identifier.doi: | https://doi.org/10.1111/jop.12741 |
| URI: | http://hdl.handle.net/1843/78180 |
| Issue Date: | 2018 |
| metadata.dc.url.externa: | https://onlinelibrary.wiley.com/doi/10.1111/jop.12741 |
| metadata.dc.relation.ispartof: | Journal of Oral Pathology & Medicine |
| Appears in Collections: | Artigo de Periódico |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Androgen receptor in salivary gland carcinoma A review of an old marker as a possible new target.pdf | 972.8 kB | Adobe PDF | View/Open |
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