1. Repositório Institucional da UFMG
  2. Publicações Científicas e Culturais
  3. Artigo de Periódico
Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/78293
Full metadata record
DC FieldValueLanguage
dc.creatorLais Alves Jacinto-Scudeiropt_BR
dc.creatorRui Rothe-Nevespt_BR
dc.creatorVanessa Brzoskowski dos Santospt_BR
dc.creatorGustavo Dariva Machadopt_BR
dc.creatorDaniela Burguêzpt_BR
dc.creatorMarina Martins Pereira Padovanipt_BR
dc.creatorAnnelise Ayrespt_BR
dc.creatorRafaela Soares Rechpt_BR
dc.creatorCarelis González-Salazarpt_BR
dc.creatorMarcondes Cavalcante França Juniorpt_BR
dc.creatorJonas Alex Morales Sautept_BR
dc.creatorMaira Rozenfeld Olchikpt_BR
dc.date.accessioned2024-11-26T15:14:16Z-
dc.date.available2024-11-26T15:14:16Z-
dc.date.issued2023-
dc.citation.volume78pt_BR
dc.identifier.doihttps://doi.org/10.1016/j.clinsp.2022.100128pt_BR
dc.identifier.issn1980-5322pt_BR
dc.identifier.urihttp://hdl.handle.net/1843/78293-
dc.description.resumoObjective: To describe the speech pattern of patients with hereditary Spastic Paraplegia type 4 (SPG4) and correlated it with their clinical data. Methods: Cross-sectional study was carried out in two university hospitals in Brazil. Two groups participated in the study: the case group (n = 28) with a confirmed genetic diagnosis for SPG4 and a control group (n = 17) matched for sex and age. The speech assessment of both groups included: speech task recording, acoustic analysis, and auditory- perceptual analysis. In addition, disease severity was assessed with the Spastic Paraplegia Rating Scale (SPRS). Results: In the auditory-perceptual analysis, 53.5% (n = 15) of individuals with SPG4 were dysarthric, with mild to moderate changes in the subsystems of phonation and articulation. On acoustic analysis, SPG4 subjects’ performances were worse in measurements related to breathing (maximum phonation time) and articulation (speech rate, articulation rate). The articulation variables (speech rate, articulation rate) are related to the age of onset of the first motor symptom. Conclusion: Dysarthria in SPG4 is frequent and mild, and it did not evolve in conjunction with more advanced motor diseases. This data suggest that diagnosed patients should be screened and referred for speech therapy evaluation and those pathophysiological mechanisms of speech involvement may differ from the length-dependent degeneration of the corticospinal tract.pt_BR
dc.format.mimetypepdfpt_BR
dc.languageengpt_BR
dc.publisherUniversidade Federal de Minas Geraispt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.departmentFALE - FACULDADE DE LETRASpt_BR
dc.publisher.initialsUFMGpt_BR
dc.relation.ispartofClinicspt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectSpastic Paraplegia, Hereditarypt_BR
dc.subjectDysarthriapt_BR
dc.subjectSpeechpt_BR
dc.subjectSpeech Disorderspt_BR
dc.subject.otherDistúrbios da falapt_BR
dc.subject.otherDistúrbios da articulaçãopt_BR
dc.titleDysarthria in hereditary spastic paraplegia type 4pt_BR
dc.typeArtigo de Periódicopt_BR
dc.url.externahttps://www.sciencedirect.com/science/article/pii/S1807593222033294pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-8896-8862pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-2322-3499pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-3388-3666pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0001-9120-6562pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-3205-3660pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-3207-0180pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-2300-682Xpt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-0898-2419pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0003-1141-6573pt_BR
dc.identifier.orcidhttps://orcid.org/0000-0002-8732-9225pt_BR
Appears in Collections:Artigo de Periódico

Files in This Item:
File Description SizeFormat 
Dysarthria in hereditary spastic paraplegia type 4.pdf256.2 kBAdobe PDFView/Open
Show simple item record


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.