Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/78478
Type: Artigo de Periódico
Title: Lymphomas Affecting the Sublingual Glands: A Clinicopathological Study
Authors: Gabriela Ribeiro de Araújo
Hélder Antônio Rebelo Pontes
Bruno Augusto Benevenuto de Andrade
Ciro Dantas Soares
Ricardo Santiago Gomez
Felipe Paiva Fonseca
Ana Luísa Morais-Perdigão
Cinthia Verónica Bardález Lopez de Cáceres
Márcio Ajudarte Lopes
José Manuel Aguirre-urizar
Roman Carlos
Elena María José Román Tager
Willie F. P. Van Heerden
Liam Robinson
Abstract: Background Lymphomas afecting the sublingual glands are extremely rare and very few case reports are currently available. Therefore, the aim of the current study is to describe the clinicopathological features of a series of lymphomas involving the sublingual glands. Methods Cases diagnosed in four pathology services were assessed and the formalin-fxed parafn-embedded tissue blocks were retrieved for diagnosis confrmation. Clinical data were obtained from patients’ medical fles. Results We obtained seven cases of lymphomas in the sublingual glands, representing two follicular lymphomas, two difuse large B cell lymphomas not otherwise specifed (DLBCL NOS), two extranodal marginal zone B cell lymphoma of mucosa associated lymphoid tissue (MALT lymphomas) and one mantle cell lymphoma (MCL). In all cases the tumor cells infltrated the glandular parenchyma, although in two of them the neoplastic cells were located more superfcially and permeated the glandular acini and ducts. Clinically, the tumors presented as asymptomatic nodules and two patients (afected by DLBCL NOS and MCL) died, while the other fve patients remained alive at last follow-up. Conclusion Lymphomas afecting the sublingual glands are usually of the mature B cell lineage, often represent low-grade subtypes and may clinically resemble other more common lesions in the foor of the mouth like salivary gland tumors.
Subject: Odontologia
Linfoma
language: eng
metadata.dc.publisher.country: Brasil
Publisher: Universidade Federal de Minas Gerais
Publisher Initials: UFMG
metadata.dc.publisher.department: FAO - DEPARTAMENTO DE CLÍNICA
Rights: Acesso Restrito
metadata.dc.identifier.doi: https://doi.org/10.1007/s12105-022-01489-8
URI: http://hdl.handle.net/1843/78478
Issue Date: Mar-2023
metadata.dc.url.externa: https://link.springer.com/article/10.1007/s12105-022-01489-8#citeas
metadata.dc.relation.ispartof: Head and Neck Pathology
Appears in Collections:Artigo de Periódico

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