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http://hdl.handle.net/1843/79448| Type: | Artigo de Periódico |
| Title: | Dynamics of early establishment of SARS-CoV-2 VOC Omicron lineages in Minas Gerais, Brazil |
| Authors: | Mariane Talonde Menezes Valquíria Reis-souza Bibiana Santos Danielle Alves Gomes Zauli Aline Brito de Lima Cristiane de Brito Mendonça Luige Biciati Alvim Joice do Prado Silva Frederico Scott Varella Malta Alessandro Clayton de Souza Ferreira Nuno Faria Filipe Romero Rebello Moreira Renato Santana de Aguiar Charles Whittaker Franciele Martins Santos Daniel Costa Queiroz Victor Geddes Paula Luize Camargos Fonseca Jaqueline Góes de Jesus Franciane Mendes-oliveira |
| Abstract: | Brazil is one of the nations most affected by Coronavirus disease 2019 (COVID-19). The introduction and establishment of new virus variants can be related to an increase in cases and fatalities. The emergence of Omicron, the most modified SARS-CoV-2 variant, caused alarm for the public health of Brazil. In this study, we examined the effects of the Omicron introduction in Minas Gerais (MG), the second-most populous state of Brazil. A total of 430 Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) samples from November 2021 to June 2022 from Belo Horizonte (BH) city were sequenced. These newly sequenced genomes comprise 72% of all previously available SARS-CoV-2 genomes for the city. Evolutionary analysis of novel viral genomes reveals that a great diversity of Omicron sublineages have circulated in BH, a pattern in-keeping with observations across Brazil more generally. Bayesian phylogeographic reconstructions indicate that this diversity is a product of a large number of international and national importations. As observed previously, São Paulo state is shown as a significant hub for viral spread throughout the country, contributing to around 70% of all viral Omicron introductions detected in MG. |
| Subject: | SARS-CoV-2 Vírus Genética |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | ICB - DEPARTAMENTO DE ZOOLOGIA |
| Rights: | Acesso Aberto |
| metadata.dc.identifier.doi: | https://www.mdpi.com/1999-4915/15/2/585 |
| URI: | http://hdl.handle.net/1843/79448 |
| Issue Date: | 2023 |
| metadata.dc.url.externa: | https://doi.org/10.3390/v15020585 |
| metadata.dc.relation.ispartof: | Viruses |
| Appears in Collections: | Artigo de Periódico |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Dynamics of Early Establishment of SARS-CoV-2 VOC Omicron Lineages in Minas Gerais, Brazil.pdf | 1.73 MB | Adobe PDF | View/Open |
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