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http://hdl.handle.net/1843/79498| Type: | Artigo de Periódico |
| Title: | Melanotic neuroectodermal tumour of infancy of the jaws: an analysis of diagnostic features and treatment |
| Authors: | Bruno Ramos Chrcanovic Ricardo Santiago Gomez |
| Abstract: | The purpose of this study was to integrate the available published data on melanotic neuroectodermal tumour of infancy (MNTI) of the jaws into a comprehensive analysis of its clinical/radiological features, with emphasis on the predictive factors associated with recurrence. Eligibility criteria included publications with sufficient clinical/radiological/histological information to confirm the diagnosis. A total of 288 publications reporting 429 MNTI cases were included. MNTIs were slightly more prevalent in males and markedly more prevalent in the maxilla. Most of the lesions were asymptomatic, presenting cortical bone perforation and tooth displacement. Nine lesions were malignant, with metastasis in five cases. Enucleation was the predominant treatment (67.2%), followed by marginal (18.4%) and segmental resection (6.1%). Eighty-one of 356 lesions (22.8%) recurred. Recurrence rates were 61.5% for curettage, 25.3% for enucleation alone, 16.2% for enucleation+curettage, 20.0% for enucleation+peripheral osteotomy, 11.3% for marginal resection, 10.0% for segmental resection, 30.0% for chemotherapy, and 33.3% for radiotherapy. Enucleation and resection presented significantly lower recurrence rates in comparison to curettage. Curettage appears not to be the best form of treatment, due to its high recurrence rate. As resection (either marginal or segmental) is associated with higher morbidity, enucleation with or without complementary treatment (curettage or peripheral osteotomy) would appear to be the most indicated therapy. |
| Subject: | Neoplasms Maxilla Tooth Avulsion Neuroectodermal Tumor Melanotic Osteotomy |
| language: | eng |
| metadata.dc.publisher.country: | Brasil |
| Publisher: | Universidade Federal de Minas Gerais |
| Publisher Initials: | UFMG |
| metadata.dc.publisher.department: | FAO - DEPARTAMENTO DE CLÍNICA |
| Rights: | Acesso Restrito |
| metadata.dc.identifier.doi: | https://doi.org/10.1016/j.ijom.2018.08.006 |
| URI: | http://hdl.handle.net/1843/79498 |
| Issue Date: | Jan-2019 |
| metadata.dc.url.externa: | https://www.ijoms.com/article/S0901-5027(18)30323-0/abstract |
| metadata.dc.relation.ispartof: | International Journal of Oral and Maxillofacial Surgery |
| Appears in Collections: | Artigo de Periódico |
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