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http://hdl.handle.net/1843/83425| Tipo: | Artigo de Periódico |
| Título: | Embryonal rhabdomyosarcoma (botryoid subtype) affecting the buccal mucosa |
| Autor(es): | John Lennon Silva Cunha Francisco de Assis Almeida Lima-Júnior Wilson Déda Gonçalves Júnior Thiago de Santana Santos Ericka Janine Dantas da Silveira Sílvia Ferreira de Sousa Ricardo Luiz Cavalcanti de Albuquerque Junior |
| Resumo: | Rhabdomyosarcoma (RMS) is a rare oral malignant soft tissue tumor whose pathological features may influence the clinical behavior, treatment and prognosis of the lesion. We report a case of a 13-year-old female patient, presenting an asymptomatic polypoid swelling in the left buccal mucosa that was approximately 2.5 cm in diameter and 3 months evolution. The presumptive diagnosis was fibrous hyperplasia and an excisional biopsy was carried out. Pathologic analysis revealed proliferation of predominantly ovoid cells, with eosinophilic cytoplasm and pleomorphic nuclei, arranged in subepithelial cambium layer. The mucosal surface presented a papillary-verrucous appearance. Immunohistochemical analysis revealed intense positivity for desmin, myogenin and Ki-67. The diagnosis was of embryonal RMS (botryoid variant). The patient was subjected to complementary chemotherapy and radiotherapy, with no evidence of recurrence or metastatic disease after 12 months follow-up. A discussion on the clinical, histopathological, immunohistochemical and therapeutic aspects of botryoid RMS will be provided. |
| Assunto: | Radiotherapy Head and neck neoplasms Rhabdomyosarcoma Desmin Myogenin Ki-67 antigen Consolidation chemotherapy Immunohistochemistry Rhabdomyosarcoma, embryonal Cell proliferation |
| Idioma: | eng |
| País: | Brasil |
| Editor: | Universidade Federal de Minas Gerais |
| Sigla da Instituição: | UFMG |
| Departamento: | FAO - DEPARTAMENTO DE CLÍNICA ICB - DEPARTAMENTO DE PATOLOGIA |
| Tipo de Acesso: | Acesso Restrito |
| Identificador DOI: | https://doi.org/10.1007/s12105-018-0957-8 |
| URI: | http://hdl.handle.net/1843/83425 |
| Data do documento: | Dez-2019 |
| metadata.dc.url.externa: | https://link.springer.com/article/10.1007/s12105-018-0957-8 |
| metadata.dc.relation.ispartof: | Head and Neck Pathology |
| Aparece nas coleções: | Artigo de Periódico |
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