Please use this identifier to cite or link to this item: http://hdl.handle.net/1843/83817
Type: Artigo de Periódico
Title: Patients hospitalized with active tuberculosis and covid-19 coinfection: a matched case-control from the brazilian covid-19 registry
Authors: Rafael Lima Rodrigues de Carvalho
Fernando Anschau
Jose Miguel Chatkin
Karen Brasil Ruschel
Marcelo Carneiro
Neimy Ramos de Oliveira
Pedro Gibson Paráiso
Rubia Laura Oliveira Aguiar
Genna Maíra Santos Grizende
Milena Soriano Marcolino
Gabriela Genta Aguiar
Jessica Fernandes Benavides Moreira
Daniella Nunes Pereira
Valeria Maria Augusto
Alexandre Vargas Schwarzbold
Carolina Cunha Matos
Danyelle Romana Alves Rios
Felicio Roberto Costa
Abstract: Although control of Covid-19 has improved, the virus continues to cause , such as tuberculosis, that is still endemic in many countries, representing a scenario of coinfection. To compare Covid-19 clinical manifestations and outcomes between patients with active tuberculosis infection and matched controls. This is a matched case-control study based on data from the Brazilian Covid-19 Registry, in hospitalized patients aged 18 or over with laboratory confirmed Covid-19 from March 1, 2020, to March 31, 2022. Cases were patients with tuberculosis and controls were Covid-19 patients without tuberculosis. From 13,636 Covid-19, 36 also had active tuberculosis (0.0026%). Pulmonary fibrosis (5.6% vs 0.0%), illicit drug abuse (30.6% vs 3.0%), alcoholism (33.3% vs 11.9%) and smoking (50.0% vs 9.7%) were more common among patients with tuberculosis. They also had a higher frequency of nausea and vomiting (25.0% vs 10.4%). There were no significant differences in in-hospital mortality, mechanical ventilation, need for dialysis and ICU stay. Patients with TB infection presented a higher frequency of pulmonary fibrosis, abuse of illicit drugs, alcoholism, current smoking, symptoms of nausea and vomiting. The outcomes were similar between them.
Subject: Covid-19
Hospitalization
Infectious Disease Medicine
Prognosis
Tuberculosis
language: eng
metadata.dc.publisher.country: Brasil
Publisher: Universidade Federal de Minas Gerais
Publisher Initials: UFMG
metadata.dc.publisher.department: MED - DEPARTAMENTO DE CLÍNICA MÉDICA
Rights: Acesso Aberto
metadata.dc.identifier.doi: https://doi.org/10.1590/0001-3765202420230791
URI: http://hdl.handle.net/1843/83817
Issue Date: 2024
metadata.dc.url.externa: https://www.scielo.br/j/aabc/a/LZkLNbdr8tdrzkVBfpYTJWx/?lang=en
metadata.dc.relation.ispartof: Anais da Academia Brasileira de Ciências
Appears in Collections:Artigo de Periódico

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