Fatores maternos e obstétricos que interferem na celularidade do sangue de cordão umbilical: revisão integrativa

Abstract

The stem cell transplantation is a therapeutic option that seeks reestablish the medullar function in patients with neoplasic disease or bone marrow dysfunction. The blood of umbilical cord is today an alternative for this type of transplant. The number of cells (cellularity) infused in the patient is associated with a better result of the transplant. This work, had as objective, identify in literature the factors maternal and obstetric that interfere in cellularity from umbilical cord blood. The evidence-based practice was used as theoretical referential and a revision integrative literature as methodological referential . Were included articles with complete texts available online, in english, Portuguese and Spanish among the years 2008-2013 and only studies performed in humans. To the search the descriptors indexed: umbilical cord blood (umbilical cord blood), pregnancy (pregnancy), cellular counting (cell count) and a descriptor unindexed obstetric factors (obstetric factors) were udsed. After reading 14 articles were selected. Gestational age, the type of childbirth and placental weight in the work studied would be the factors maternal and obstetric cited, which more would influence cellularity umbilical cord. Stands in the findings of authors the age gestational interferes positively, childbirth vaginal improves cellularity TNC and childbirth cesarean improve the cell count. Not were considered the techniques and protocols used for counting cell. Through knowledge and of evidence is possible instrumentalize professionals, including nurses, to refine the collection work of the umbilical cord blood and obtain the best material for achieve results increasingly satisfactory in cell transplantation hematopoietic stem.