Odontogeriatria: interações medicamentosas

Abstract

This study aimed to identify the drugs prescribed in dentistry creating risks of drug interactions with drugs that are being employed for the control of systemic diseases common in old age. We conducted a literature search in the Literatura Latino-Americana e do Caribe em Ciências da Saúde LILACs , Scientific Electronic Library Online SCIELO and manuals of the Ministry of Health and State Health Department associated with the identification of the main drugs used in treating diseases commonly associated with old age such as diabetes mellitus, hypertension, depression, rheumatoid arthritis and other diseases. Several drugs for the control of systemic diseases predispose patients to risk of drug interactions. As a result of the research it was found that the use of no-steroidal anti-inflammatory drugs (AINEs) are related to the attenuation of the antihypertensive effects of inhibitors of angiotensin-converting enzyme, beta-blockers and diuretics; potentiation of adverse effects of lithium, the effect of anticoagulant and antiplatelet effects toxic antimetabolites. The analgesic dipyrone when interacting with chlorpromazine, an antipsychotic, because of increased adverse reactions. The antibiotics prescribed by dentists in general increases blood concentrations by a deficit in renal excretion of litio, digoxina, tranquilizers (triazolan and midazolan)), theofilina, oral anticoagulants and metotrexato. New drugs with new action spectra are delivered each year, creating a constant need to familiarize the professional with the current medical literature allowing prevent iatrogenic responses associated with the use of several drugs at once. It is concluded that dental professionals should have knowledge of the patterns of the drugs and prescriptions for the elderly, since it constitutes an important measure to avoid drug interactions in drug therapy proposal.