Adequação da técnica de hemodiálise em eqüinos hígidos: avaliação clínica e laboratorial

Abstract

The goal of this study was to promote hemodialysis adequacy in equine. Four experimental groups was formed, with six horses wich following the treatments: Group I: horses submited to unilateral central venous catheter and a sedation protocol (control group); Group II: horses submited to unilateral central venous double lumen catheter and one session of six hours hemodialysis; Group III: horses submited to unilateral central venous double lumen catheter and two sessions of six hours hemodialysis; Group IV: horses submited to bilateral central venous mono lumen catheter and one session of six hours hemodialysis. Xilazine 10% (0,1 ml/50 kg) associated with acepromazine 2% (0,1 ml/50 kg) was done by venous rote for sadation. Two hollow fiber, low flux polyssulfone of 1,8m2 was used in serie connexion. The mean blood flux was 319,18 ± 97,41 ml/min. Antiocoagulation was performed with sodium heparin, 100 UI/kg for primming and at the dose of 53,86 ± 18,61 UI/kg/hr. The clinicla parameters approach was not changged by dialysis, neither venous pressure or electrocardiography analysis. In hematologic evaluation was seen decrease in erythrocytes, MCHC, MCH, MCV and leucocytes. High decrease in platelet number occurred by the effect of hemodialysis plus heparin. Values for acid-base balance did not suffer pathologic changes, and serum biochemistry analysis shown hiperglicaemia at 24 hours post dialysis in groups II and III. The urine analysis shown no difference by dialitic procedure. We concluded that the best vascular access was performed with ths double lumen catheter and the hemodialysis may be used in equine practice, sice high performance dializer were used in six hours session.