Determination of the dose rate constant through Monte Carlo simulations with voxel phantoms

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dc.creatorAbner Duarte Soares
dc.creatorLucas Paixão Reis
dc.creatorAlessandro Facure
dc.date.accessioned2023-08-18T23:45:54Z
dc.date.accessioned2025-09-08T23:55:27Z
dc.date.available2023-08-18T23:45:54Z
dc.date.issued2018-12-23
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1002/mp.13181
dc.identifier.issn00942405
dc.identifier.urihttps://hdl.handle.net/1843/57959
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofMedical Physics
dc.rightsAcesso Restrito
dc.subjectDosagem
dc.subjectMétodo de Monte Carlo
dc.subject.otherBiodistribution
dc.subject.otherBody attenuation
dc.subject.otherDose rate constant
dc.subject.otherEffective half-life
dc.subject.otherMonte Carlo simulation
dc.subject.otherVoxel phantoms
dc.titleDetermination of the dose rate constant through Monte Carlo simulations with voxel phantoms
dc.typeArtigo de periódico
local.citation.epage5292
local.citation.issue11
local.citation.spage5283
local.citation.volume45
local.description.resumoPurpose: The main goal of this study was to determine the dose rate constant of radionuclides used in Nuclear Medicine when they are biodistributed in humans. The secondary goal was to calculate the effective half-life for the same radionuclides in order to determine the realistic dose due to the incorporation of these nuclides for a variety of reasons.Methods: Anthropomorphic voxel phantoms, with characteristics based on ICRP-110 were consid ered and the biodistributions of radionuclides were simulated using the Monte Carlo code MCNPX.In addition, the effective half-lives for all simulated radionuclides were calculated.Results: The results for the dose rate constant, taking into account the patient body attenuation,showed no correlation between the biodistribution of the radionuclide and the energy of the radiationemitted. Body attenuation ranged between 6.7% and 94.1%. Also, the priority angle of radiation emission was determined. The values found for the body attenuation agree with the literature, corroborating the calculation of the body dose rate constant.Conclusions: The results for the body dose rate constant calculated in this work, for 30 radionu clides and 57 radiopharmaceuticals, and their effective half-lives, may be used to estimate the dose emitted by a person who has incorporated a radionuclide in the Nuclear Medicine activity range. This dose will be optimized when the body dose rate constant and the effective half-life determined in this study are used together with dose reduction factors
local.identifier.orcidhttps://orcid.org/0000-0003-0579-309X
local.publisher.countryBrasil
local.publisher.departmentMED - DEPARTAMENTO DE ANATOMIA E IMAGEM
local.publisher.initialsUFMG
local.url.externahttps://aapm.onlinelibrary.wiley.com/doi/full/10.1002/mp.13181

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