Oral bilateral collagenous fibroma: a previously unreported case and literature review

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dc.creatorAna Carolina Uchoa Vasconcelos
dc.creatorAna Paula Neutzling Gomes
dc.creatorSandra Beatriz Chaves Tarquinio
dc.creatorEduardo Rodrigues Abduch
dc.creatorRicardo Alves de Mesquita
dc.creatorKarine Duarte Silva
dc.date.accessioned2024-10-15T16:01:38Z
dc.date.accessioned2025-09-08T23:59:29Z
dc.date.available2024-10-15T16:01:38Z
dc.date.issued2018-01-01
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.4317/jced.54123
dc.identifier.issn1989-5488
dc.identifier.urihttps://hdl.handle.net/1843/77448
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofJournal of Clinical and Experimental Dentistry
dc.rightsAcesso Aberto
dc.subjectConnective tissue
dc.subjectMouth diseases
dc.subjectMouth neoplasms
dc.subjectDiagnosis, oral
dc.subjectPathology, oral
dc.subjectFibroma, desmoplastic
dc.subjectPalate, hard
dc.subjectClinical study
dc.subjectTissues
dc.subject.otherConnective tissue
dc.subject.otherMouth diseases
dc.subject.otherMouth neoplasms
dc.subject.otherOral diagnosis
dc.subject.otherOral pathology
dc.titleOral bilateral collagenous fibroma: a previously unreported case and literature review
dc.typeArtigo de periódico
local.citation.epagee99
local.citation.issue1
local.citation.spagee96
local.citation.volume10
local.description.resumoCollagenous fibroma, also known as desmoplastic fibroblastoma, is a rare benign slow growing tumor particularly uncommon in the oral cavity. The aim of this study was to analyze the clinical and histopathological features of an oral collagenous fibroma as well as to compare this data with those reported in an English-literature review. The thirteenth case of collagenous fibroma in the oral cavity and the first to present clinically as a bilateral mass was described. A 48-years-old female patient was referred to a School of Dentistry, complaining about an asymptomatic swelling on the hard palate, lasting around ten years. The intraoral examination revealed two well-defined mass, bilaterally in the hard palate. An excisional biopsy was performed. Microscopically, the connective tissue consisted of dense collagen bundles in which were seen scarcely distributed spindle-shaped to stellate fibroblastic cells. Blood vessels were few, as well as inflammatory cells. Immunohistochemical staining was positive for vimentin, α-smooth muscle actin and factor XIIIa and negative for S-100, CD68, CD34, HHF35, desmin and AE1/AE3. The patient remains disease-free 24 months after excision. In conclusion, oral collagenous fibroma should be included in the differential diagnosis of bilateral sessile nodules in the oral cavity.
local.identifier.orcidhttps://orcid.org/0000-0001-6560-9536
local.identifier.orcidhttps://orcid.org/0000-0003-1496-4137
local.identifier.orcidhttps://orcid.org/0000-0003-3207-4007
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICA
local.publisher.initialsUFMG
local.url.externahttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899808/

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