Intravenous ceftriaxone for syphilitic uveitis

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dc.creatorFernanda A.agostini
dc.creatorRafael p. Queiroz
dc.creatorDanuza o. m. Azevedo
dc.creatorJuliana f. Henriques
dc.creatorWesley Ribeiro Campos
dc.creatorDaniel v. Vasconcelos-santos
dc.date.accessioned2023-06-06T21:14:54Z
dc.date.accessioned2025-09-08T23:08:18Z
dc.date.available2023-06-06T21:14:54Z
dc.date.issued2017-05-04
dc.format.mimetypepdf
dc.identifier.doi10.1080/09273948.2017.1311926
dc.identifier.issn09273948
dc.identifier.urihttps://hdl.handle.net/1843/54627
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofOcular Immunology and Inflammation
dc.rightsAcesso Restrito
dc.subjectCeftriaxona
dc.subjectMultimodal imagens
dc.subjectNeurossífilis
dc.subjectSífilis
dc.subjectUveíte
dc.subject.otherCeftriaxone
dc.subject.otherMultimodal imaging
dc.subject.otherNeurosyphilis
dc.subject.otherSyphilis
dc.subject.otherUveitis
dc.titleIntravenous ceftriaxone for syphilitic uveitis
dc.typeArtigo de periódico
local.citation.epage1065
local.citation.issue7
local.citation.spage1059
local.citation.volume26
local.description.resumoPurpose: Report of clinical/multimodal imaging outcomes of patients with syphilitic uveitis alternatively treated with intravenous(IV) ceftriaxone, due to unavailability of penicillin G. Methods: Chart review of all cases of syphilitic uveitis presenting to Hospital São Geraldo/HC-UFMG and treated with intravenous ceftriaxone, between January and August 2014. Clinical, serological and ophthalmological data were collected. Results: Twelve consecutive patients with syphilitic uveitis receiving IV ceftriaxone were identified. All 24 eyes had active intraocular inflammation on clinical examination. All patients received IV ceftriaxone (2–4g daily) for 14–21 days, supplemented with oral corticosteroid as needed in 9 patients (75%), after documented clinical response. Improvement in intraocular inflammation was seen in all 24 eyes, with median best-corrected visual acuity (BCVA) increasing from 20/50 to 20/20, after a mean follow-up of 5.3 months. Conclusion: IV ceftriaxone may be an effective alternative for treatment of syphilitic uveitis, in the setting of unavailability of penicillin G.
local.publisher.countryBrasil
local.publisher.departmentMED - DEPARTAMENTO DE OFTALMOLOGIA E OTORRINOLARINGOLOGIA
local.publisher.initialsUFMG
local.url.externahttps://www.tandfonline.com/doi/full/10.1080/09273948.2017.1311926

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