Contributions of birthweight, annualised weight gain and BMI to back pain in adults: a population-based co-twin control study of 2754 australian twins

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dc.creatorHércules Ribeiro Leite
dc.creatorAmabile Borges Dario
dc.creatorAlison Harmer
dc.creatorVinícius Cunha de Oliveira
dc.creatorManuela Loureiro Ferreira
dc.creatorLucas Calais Ferreira
dc.creatorPaulo Henrique Ferreira
dc.date.accessioned2022-07-06T17:18:05Z
dc.date.accessioned2025-09-08T23:49:21Z
dc.date.available2022-07-06T17:18:05Z
dc.date.issued2019
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.1007/s00586-018-5850-3
dc.identifier.issn1432-0932
dc.identifier.urihttps://hdl.handle.net/1843/42973
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofEuropean Spine Journal
dc.rightsAcesso Aberto
dc.subjectPeso ao nascer
dc.subjectÍndice de massa corporal
dc.subjectGêmeos
dc.subjectDor nas costas
dc.subjectGenética
dc.subject.otherBirthweight
dc.subject.otherBMI
dc.subject.otherTwins
dc.subject.otherBack pain
dc.subject.otherGenetics
dc.titleContributions of birthweight, annualised weight gain and BMI to back pain in adults: a population-based co-twin control study of 2754 australian twins
dc.typeArtigo de periódico
local.citation.epage233
local.citation.spage224
local.citation.volume28
local.description.resumoPurpose: To investigate associations between anthropometric measures (birthweight, weight gain and current BMI) and back pain; and to determine whether these associations differ between those born with low or full birthweight. Methods: The cross-sectional associations between the lifetime prevalence of back pain and anthropometric measures (birthweight, weight gain and current BMI) among 2754 adult twins were investigated in three stages: total sample; within-pair case–control for monozygotic and dizygotic twins together; and within-pair case–control analysis separated by dizygotic and monozygotic. Results were expressed as odds ratios (OR) and 95% confidence intervals (CI). Results: Birthweight was not associated with back pain (OR 0.99; 95% CI 0.99–1.00), but a weak association was found between weight gain (OR 1.01; CI 1.00–1.01) or current BMI (OR 1.02; 95% CI 1.00–1.05) and back pain in the total sample analysis. These associations did not remain significant after adjusting for genetics. The associations did not differ between those whose were born with low or full birthweight. Conclusion: Birthweight was not associated with prevalence of back pain in adulthood. Weight gain and current BMI were weakly associated with back pain prevalence in the total sample analysis but did not differ between those born with low or full birthweight. However, the small-magnitude association only just achieved significance and appeared to be confounded by genetics and the early shared environment. Our results suggest that a direct link between these predictors and back pain in adults is unlikely.
local.identifier.orcidhttp://orcid.org/0000-0001-8977-8131
local.identifier.orcidhttps://orcid.org/ 0000-0002-4818-7017
local.identifier.orcidhttps://orcid.org/ 0000-0003-4877-5801
local.identifier.orcidhttps://orcid.org/ 0000-0002-8658-3774
local.publisher.countryBrasil
local.publisher.departmentEEF - DEPARTAMENTO DE FISIOTERAPIA
local.publisher.initialsUFMG
local.url.externahttps://link.springer.com/article/10.1007/s00586-018-5850-3

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