Brazilian arnicas: bioactive compounds, pharmacological properties, potential use and clinical applications

dc.creatorBarbhara Mota Marinho
dc.creatorCaroline Honaiser Lescano
dc.creatorSérgio Henrique Sousa Santos
dc.date.accessioned2024-10-09T18:43:17Z
dc.date.accessioned2025-09-08T23:56:00Z
dc.date.available2024-10-09T18:43:17Z
dc.date.issued2023-07-01
dc.description.sponsorshipCNPq - Conselho Nacional de Desenvolvimento Científico e Tecnológico
dc.description.sponsorshipFAPEMIG - Fundação de Amparo à Pesquisa do Estado de Minas Gerais
dc.description.sponsorshipCAPES - Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
dc.identifier.doihttps://doi.org/10.1007/s11101-023-09884-x
dc.identifier.issn1572-980X
dc.identifier.urihttps://hdl.handle.net/1843/77340
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofPhytochemistry Reviews
dc.rightsAcesso Restrito
dc.subjectPlantas medicinais
dc.subjectArnica
dc.subjectAgentes antiinflamatórios
dc.subjectAnalgésicos
dc.subjectFitoterapia
dc.subjectEtnofarmacologia
dc.subjectFlavonóides
dc.subjectFenóis
dc.subjectTerpenos
dc.titleBrazilian arnicas: bioactive compounds, pharmacological properties, potential use and clinical applications
dc.typeArtigo de periódico
local.citation.epage280
local.citation.spage245
local.citation.volume23
local.description.resumoBrazilian arnicas belong to the Asteraceae family and can be mainly found in the Brazilian biome Cerrado (savanna) but also Caatinga, Atlantic Forest, Pampa, Pantanal, and Amazonia Forest. The plant’s leaves, roots, inflorescences, and flowers have demonstrated high medicinal potential use as evidenced by recent studies. The Brazilian arnica species were selected based on their ethnopharmacological representativeness, with the 9 most relevant species being identified: Calea uniflora Less, Chaptalia nutans (L.) Polák., Lychnophora ericoides Mart, L. pinaster Mart. and L. salicifolia Mart, Porophyllum ruderale (Jacq.) Cass., Pseudobrickellia brasiliensis (Spreng.) R.M. King & H. Rob. Solidago chilensis Meyen, Sphagneticola trilobata (L.) Pruski. Brazilian arnicas species have many pharmacological/bioactive constituents such as flavonoids, phenolic compounds, and terpenoids, especially monoterpenes, and sesquiterpenes. Experimental in vitro and in vivo studies indicate its benefits to prevent, improve and treat human conditions or diseases with several beneficial effects such as anti-inflammatory, analgesic, antiedematogenic, antimicrobial, antioxidant, trypanocidal, and leishmanicidal activity. Arnicas extracts and their bioactive compounds have been suggested as useful tools in the industry, for example, in topical formulations and green chemistry. Like many other native plants spread throughout Brazil, arnicas have a high functional potential that needs further exploration. In this context, the present review aims to describe the potential use of Brazilian arnicas, highlighting their geographic distribution, uses in traditional medicine, bioactive composition, health effects, and potential applications.
local.publisher.countryBrasil
local.publisher.departmentICA - INSTITUTO DE CIÊNCIAS AGRÁRIAS
local.publisher.initialsUFMG
local.url.externahttps://link.springer.com/article/10.1007/s11101-023-09884-x

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