Central odontogenic fibroma: an international multicentric study of 62 cases

Página do item simplificado
dc.creatorAna Luiza Oliveira Corrêa Roza
dc.creatorRicardo Alves Mesquita
dc.creatorFelipe Paiva Fonseca
dc.creatorAline Corrêa Abrahão
dc.creatorMichelle Agostini
dc.creatorBruno Augusto Benevenuto de Andrade
dc.creatorEricka Janine Dantas da Silveira
dc.creatorRené Martínez-Flores
dc.creatorBenjamin Martínez Rondanelli
dc.creatorJavier Alberdi-Navarro
dc.creatorLiam Robinson
dc.creatorEmanuel Mendes Sousa
dc.creatorConstanza Marin
dc.creatorJosé Narciso Rosa Assunção
dc.creatorRenato Valiati
dc.creatorEduardo Rodrigues Fregnani
dc.creatorAlan Roger Santos-Silva
dc.creatorMarcio Ajudarte Lopes
dc.creatorKeith Hunter
dc.creatorSyed Ali Khurram
dc.creatorPaul Speight
dc.creatorAdalberto Mosqueda-Taylor
dc.creatorAmanda Almeida Leite
dc.creatorWillie Van Herdeen
dc.creatorRomán Carlos
dc.creatorJohn Wright
dc.creatorOslei Paes de Almeida
dc.creatorMário José Romañach
dc.creatorPablo Agustin Vargas
dc.creatorGleyson Kleber do Amaral-Silva
dc.creatorThayná Melo de Lima Morais
dc.creatorVivian Petersen Wagner
dc.creatorLauren Frenzel Schuch
dc.creatorAna Carolina Uchoa Vasconcelos
dc.creatorJosé Alcides Almeida de Arruda
dc.date.accessioned2023-11-22T19:38:42Z
dc.date.accessioned2025-09-09T00:14:02Z
dc.date.available2023-11-22T19:38:42Z
dc.date.issued2021-05
dc.identifier.doihttps://doi.org/10.1016/j.oooo.2020.08.022
dc.identifier.issn22124403
dc.identifier.urihttps://hdl.handle.net/1843/61266
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofOral Surgery Oral Medicine Oral Pathology Oral Radiology
dc.rightsAcesso Restrito
dc.subjectFibroma
dc.subjectRadiography
dc.subjectAmyloid
dc.subjectStudy characteristics
dc.subjectPathology
dc.subject.otheracesso restrito Central odontogenic fibroma: an international multicentric study of 62 cases fao clinica assunto fibroma dia 23 do10 2023 proxima busca 5 felipe paiva fonseca
dc.subject.othertítulo periódico Oral surgery oral medicine oral pathology oral radiology
dc.titleCentral odontogenic fibroma: an international multicentric study of 62 cases
dc.typeArtigo de periódico
local.citation.epage557
local.citation.issue5
local.citation.spage549
local.citation.volume131
local.description.resumoObjective: The aim of this study was to report the clinicopathologic features of 62 cases of central odontogenic fibroma (COdF). Study design: Clinical and radiographic data were collected from the records of 13 oral pathology laboratories. All cases were microscopically reviewed, considering the current World Health Organization classification of tumors and were classified according to histopathologic features. Results: There were 43 females and 19 males (average age 33.9 years; range 8-63 years). Clinically, COdF lesions appeared as asymptomatic swellings, occurring similarly in the maxilla (n = 33) and the mandible (n = 29); 9 cases exhibited palatal depression. Imaging revealed well-defined, interradicular unilocular (n = 27), and multilocular (n = 12) radiolucencies, with displacement of contiguous teeth (55%) and root resorption (46.4%). Microscopically, classic features of epithelial-rich (n = 33), amyloid (n = 10), associated giant cell lesion (n = 7), ossifying (n = 6), epithelial-poor (n = 3), and granular cell (n = 3) variants were seen. Langerhans cells were highlighted by CD1a staining in 17 cases. Most patients underwent conservative surgical treatments, with 1 patient experiencing recurrence. Conclusions: To the best of our knowledge, this study represents the largest clinicopathologic study of COdF. Most cases appeared as locally aggressive lesions located in tooth-bearing areas in middle-aged women. Inactive-appearing odontogenic epithelium is usually observed within a fibrous/fibromyxoid stroma, occasionally exhibiting amyloid deposits, multinucleated giant cells, or granular cells.
local.publisher.countryBrasil
local.publisher.departmentFAO - DEPARTAMENTO DE CLÍNICA
local.publisher.initialsUFMG
local.url.externahttps://www.sciencedirect.com/science/article/pii/S2212440320311718?via%3Dihub

Arquivos

Licença do pacote

Agora exibindo 1 - 1 de 1
Imagem de Miniatura
Nome:
License.txt
Tamanho:
1.99 KB
Formato:
Plain Text
Descrição:
Baixar

Coleções

Artigo de Periódico

Logo UFMG