Quality of life assessment among patients living with hepatosplenic schistosomiasis and schistosomal myeloradiculopathy

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dc.creatorSilvana Júnia Roriz
dc.creatorThiago Almeida Pereira
dc.creatorGuilherme Vaz de Melo Trindade
dc.creatorJúlia Fonseca de Morais Caporali
dc.creatorJosé Roberto Lambertucci
dc.date.accessioned2023-08-10T20:05:55Z
dc.date.accessioned2025-09-09T01:07:02Z
dc.date.available2023-08-10T20:05:55Z
dc.date.issued2021-06
dc.format.mimetypepdf
dc.identifier.doihttps://doi.org/10.3389/fmed.2021.629484
dc.identifier.issn2296-858X
dc.identifier.urihttps://hdl.handle.net/1843/57711
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofFrontiers in Medicine
dc.rightsAcesso Aberto
dc.subjectNeuroesquistossomose
dc.subjectEsquistossomose mansoni
dc.subjectQualidade de vida
dc.subject.otherHepatosplenic schistosomiasis
dc.subject.otherschistosomal myeloradiculopathy
dc.subject.otherSchistosomiasis mansoni
dc.subject.otherQuality of life
dc.titleQuality of life assessment among patients living with hepatosplenic schistosomiasis and schistosomal myeloradiculopathy
dc.typeArtigo de periódico
local.citation.epage8
local.citation.issue629484
local.citation.spage1
local.citation.volume8
local.description.resumoSchistosomiasis is a major public health problem in tropical areas of the world.Health-related quality of life (HRQOL) measurement is being widely used to evaluate the impact of a disease or treatment in several aspects of daily life. However, few studies evaluated the impact of severe forms of schistosomiasis on HRQOL of affected Schistosomiasis is a major public health problem in tropical areas of the world.Health-related quality of life (HRQOL) measurement is being widely used to evaluate the impact of a disease or treatment in several aspects of daily life. However, few studies evaluated the impact of severe forms of schistosomiasis on HRQOL of affected individuals and compared them to healthy controls with a similar socio-demographic background. Our aims were to evaluate the HRQOL in patients with hepatosplenic schistosomiasis (HS) and schistosomal myeloradiculopathy (SMR) and healthy volunteers (HV) and determine if clinical complications of the disease are associated with HRQOL scores. We interviewed and evaluated the HRQOL in 49 patients with HS, 22 patients with SMR, and 26 HV from an outpatient clinic of the Federal University of Minas Gerais University Hospital using the WHOQOL-BREF questionnaire. SMR and HS patients had a significantly lower overall quality of life score when comparing with the HV control group (p = 0.003 and p = 0.005, respectively). Multivariate ordinal regression model adjusted for sex, age, and educational level indicated that HS and SMR patients have three and five times more chances of having a lower quality of life than healthy volunteers (Odds Ratio 3.13 and 5.04, respectively). There was no association between complications of HS disease and quality of life scores. In contrast, worse quality of life was observed in SMR patients that presented back or leg pain, leg paresthesia, and bladder dysfunction. In conclusion, HS and SMR significantly impact the overall quality of life of the affected individuals, reinforcing the importance of efforts to control and eradicate this debilitating disease and suggesting that multidisciplinary clinical management of schistosomiasis patients would be more appropriate and could potentially improve patient’s quality of life.individuals and compared them to healthy controls with a similar socio-demographic background. Our aims were to evaluate the HRQOL in patients with hepatosplenic schistosomiasis (HS) and schistosomal myeloradiculopathy (SMR) and healthy volunteers (HV) and determine if clinical complications of the disease are associated with HRQOL scores. We interviewed and evaluated the HRQOL in 49 patients with HS, 22 patients with SMR, and 26 HV from an outpatient clinic of the Federal University of Minas Gerais University Hospital using the WHOQOL-BREF questionnaire. SMR and HS patients had a significantly lower overall quality of life score when comparing with the HV control group (p = 0.003 and p = 0.005, respectively). Multivariate ordinal regression model adjusted for sex, age, and educational level indicated that HS and SMR patients have three and five times more chances of having a lower quality of life than healthy volunteers (Odds Ratio 3.13 and 5.04, respectively). There was no association between complications of HS disease and quality of life scores. In contrast, worse quality of life was observed in SMR patients that presented back or leg pain, leg paresthesia, and bladder dysfunction. In conclusion, HS and SMR significantly impact the overall quality of life of the affected individuals, reinforcing the importance of efforts to control and eradicate this debilitating disease and suggesting that multidisciplinary clinical management of schistosomiasis patients would be more appropriate and could potentially improve patient’s quality of life.
local.identifier.orcidhttps://orcid.org/0000-0003-0544-309X
local.publisher.countryBrasil
local.publisher.departmentMED - DEPARTAMENTO DE CLÍNICA MÉDICA
local.publisher.initialsUFMG
local.url.externahttps://www.frontiersin.org/articles/10.3389/fmed.2021.629484/full

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