Estimates of the global, regional, and national morbidity, mortality, and aetiologies of diarrhoea in 195 countries: a systematic analysis for the global burden of disease study 2016

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dc.creatorChristophertroeger
dc.creatorZegeye Abebe
dc.creatorJuan Ramon Sanabria
dc.creatorBenn Sartorius
dc.creatorMonika Sawhney
dc.creatorSadaf g Sepanlou
dc.creatorMika Shigematsu
dc.creatorMekonnen Sisay
dc.creatorRanjani Somayaji
dc.creatorChandrashekhar t Sreeramareddy
dc.creatorBryan l Sykes
dc.creatorNancy Fullman
dc.creatorPeter w Gething
dc.creatorMelkamu Dedefo Gishu
dc.creatorWilliam w Godwin
dc.creatorHarish Chander Gugnani
dc.creatorShujin Cao
dc.creatorRahul Gupta
dc.creatorGessessew Bugssa Hailu
dc.creatorHamid Yimam Hassen
dc.creatorDesalegn Tsegaw Hibstu
dc.creatorSuresh Mehata
dc.creatorOlayinka s Ilesanmi
dc.creatorJost b Jonas
dc.creatorAmaha Kahsay
dc.creatorGagandeep Kang
dc.creatorAmir Kasaeian
dc.creatorYousef Saleh Khader
dc.creatorStephanie rm Zimsen
dc.creatorIbrahim a Khalil
dc.creatorEjaz Ahmad Khan
dc.creatorMuhammad Ali Khan
dc.creatorWalter Mendoza
dc.creatorYoung-ho Khang
dc.creatorNiranjan Kissoon
dc.creatorSonali Kochhar
dc.creatorKaren l Kotloff
dc.creatorai Koyanagi
dc.creatorg Anil Kumar
dc.creatorHassan Magdy Abd el Razek
dc.creatorSamuel b Albertson
dc.creatorReza Malekzadeh
dc.creatorDeborah Carvalho Malta
dc.creatorDesalegn Tadese Mengistu
dc.creatorBereket Gebremichael Menota
dc.creatorHaftay Berhane Mezgebe
dc.creatorFitsum Weldegebreal Mlashu
dc.creatorSrinivas Murthy
dc.creatorGurudatta a Naik
dc.creatorJeffery d Stanaway
dc.creatorCuong Tat Nguyen
dc.creatorGetachew Redae Taffere
dc.creatorTrang Huyen Nguyen
dc.creatorDina Nur Anggraini Ningrum
dc.creatorFelix Akpojene Ogbo
dc.creatorAndrew Toyin Olagunju
dc.creatorDeepak Paudel
dc.creatorJames a Platts-mills
dc.creatorMostafa Qorbani
dc.creatorAnwar Rafay
dc.creatorRajesh Kumar Rai
dc.creatorAniruddha Deshpande
dc.creatorNelson Alvis-guzman
dc.creatorSaleem m Rana
dc.creatorChhabi Lal Ranabhat
dc.creatorDavide Rasella
dc.creatorSarah e Ray
dc.creatorCesar Reis
dc.creatorAndre mn Renzaho
dc.creatorMohammad Sadegh Rezai
dc.creatorGeorge Mugambage Ruhago
dc.creatorSaeid Safiri
dc.creatorJoshua a Salomon
dc.creatorRoman Topor-madry
dc.creatorBach Xuan Tran
dc.creatorKald Beshir Tuem
dc.creatorKingsley Nnanna Ukwaja
dc.creatorStein Emil Vollset
dc.creatorJudd l Walson
dc.creatorMarcia r Weaver
dc.creatorKidu Gidey Weldegwergs
dc.creatorAndrea Werdecker
dc.creatorAbdulhalik Workicho
dc.creatorAzmeraw t Amare
dc.creatorMuluken Yenesew
dc.creatorBiruck Desalegn Yirsaw
dc.creatorNaohiro Yonemoto
dc.creatorMaysaa el Sayed Zaki
dc.creatorTheo Vos
dc.creatorStephen s Lim
dc.creatorMohsen Naghavi
dc.creatorChristopher jl Murray
dc.creatorAli h Mokdad
dc.creatorSimon i Hay
dc.creatorSolomon w Asgedom
dc.creatorRobert c Reiner
dc.creatorZelalem Alamrew Anteneh
dc.creatorCarl Abelardo t Antonio
dc.creatorOlatunde Aremu
dc.creatorEphrem Tsegay Asfaw
dc.creatorTesfay Mehari Atey
dc.creatorSuleman Atique
dc.creatorBrigette f Blacker
dc.creatorEuripide Frinel g Arthur Avokpaho
dc.creatorAshish Awasthi
dc.creatorHenok Tadesse Ayele
dc.creatorAleksandra Barac
dc.creatorMauricio l Barreto
dc.creatorQuique Bassat
dc.creatorSaba Abraham Belay
dc.creatorIsabela m Bensenor
dc.creatorZulfiqar a Bhutta
dc.creatorAli Bijani
dc.creatorIbrahim a Khalil
dc.creatorHailemichael Bizuneh
dc.creatorCarlos a Castañeda-orjuela
dc.creatorAbel Fekadu Dadi
dc.creatorLalit Dandona
dc.creatorRakhi Dandona
dc.creatorHuyen Phuc do
dc.creatorManisha Dubey
dc.creatorEleonora Dubljanin
dc.creatorDumessa Edessa
dc.creatorAman Yesuf Endries
dc.creatorPuja c Rao
dc.creatorBabak Eshrati
dc.creatorTamer Farag
dc.creatorGarumma Tolu Feyissa
dc.creatorKyle j Foreman
dc.creatorMohammad h Forouzanfar
dc.date.accessioned2023-04-24T21:35:37Z
dc.date.accessioned2025-09-09T01:28:55Z
dc.date.available2023-04-24T21:35:37Z
dc.date.issued2018
dc.format.mimetypepdf
dc.identifier.doi10.1016/s1473-3099(18)30362-1
dc.identifier.issn14733099
dc.identifier.urihttps://hdl.handle.net/1843/52439
dc.languageeng
dc.publisherUniversidade Federal de Minas Gerais
dc.relation.ispartofThe Lancet
dc.rightsAcesso Aberto
dc.subjectMortalidade
dc.subjectCarga Viral de Doença
dc.subjectEpidemiologia
dc.subject.otherMortality
dc.subject.otherGlobal Burden Disease
dc.subject.otherEpidemiology
dc.titleEstimates of the global, regional, and national morbidity, mortality, and aetiologies of diarrhoea in 195 countries: a systematic analysis for the global burden of disease study 2016
dc.typeArtigo de periódico
local.citation.epage1228
local.citation.issue11
local.citation.spage1211
local.citation.volume18
local.description.resumoBackground The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 provides an up-to-date analysis of the burden of diarrhoea in 195 countries. This study assesses cases, deaths, and aetiologies in 1990–2016 and assesses how the burden of diarrhoea has changed in people of all ages.Methods We modelled diarrhoea mortality with a Bayesian hierarchical modelling platform that evaluates a wide range of covariates and model types on the basis of vital registration and verbal autopsy data. We modelled diarrhoea incidence with a compartmental meta-regression tool that enforces an association between incidence and prevalence, and relies on scientific literature, population representative surveys, and health-care data. Diarrhoea deaths and episodes were attributed to 13 pathogens by use of a counterfactual population attributable fraction approach. Diarrhoea risk factors are also based on counterfactual estimates of risk exposure and the association between the risk and diarrhoea. Each modelled estimate accounted for uncertainty.Findings In 2016, diarrhoea was the eighth leading cause of death among all ages (1 655944 deaths, 95% uncertainty interval [UI] 1244 073–2366 552) and the fifth leading cause of death among children younger than 5 years (446 000 deaths, 390 894–504 613). Rotavirus was the leading aetiology for diarrhoea mortality among children younger than 5 years (128 515 deaths, 105138–155 133) and among all ages (228 047 deaths, 183 526–292737). Childhood wasting (low weight-for-height score), unsafe water, and unsafe sanitation were the leading risk factors for diarrhoea, responsible for 80·4% (95% UI 68·2–85·0), 72·1% (34·0–91·4), and 56·4% (49·3–62·7) of diarrhoea deaths in children younger than 5 years, respectively. Prevention of wasting in 1762 children (95% UI 1521–2170) could avert one death from diarrhoea. Interpretation Substantial progress has been made globally in reducing the burden of diarrhoeal diseases, driven by decreases in several primary risk factors. However, this reduction has not been equal across locations, and burden among adults older than 70 years requires attention.
local.identifier.orcidhttps://orcid.org/0000-0002-8214-5734
local.publisher.countryBrasil
local.publisher.departmentENF - DEPARTAMENTO DE ENFERMAGEM MATERNO INFANTIL E SAÚDE PÚBLICA
local.publisher.initialsUFMG
local.url.externahttps://doi:10.1016/s1473-3099(18)30362-1

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